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Molecular study of selected differentially expressed genes in nasopharyngeal carcinoma

Nasopharyngeal Carcinoma (NPC) occurs as a consequence of multiple molecular events induced by environmental factors and Epstein-Barr virus (EBV) infections. The neoplastic processes may involve alterations of the tumor suppressor genes and oncogenes by genetic damage and interference with the norma...

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Main Author: Chua, Suk Ngo
Format: Thesis
Language:English
Published: Universiti Malaysia Sarawak, (UNIMAS) 2011
Subjects:
RB Pathology
Online Access:http://ir.unimas.my/id/eprint/13304/1/Chua%20Suk%20Ngo%20ft.pdf
http://ir.unimas.my/id/eprint/13304/
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spelling my.unimas.ir.133042023-05-08T07:28:27Z http://ir.unimas.my/id/eprint/13304/ Molecular study of selected differentially expressed genes in nasopharyngeal carcinoma Chua, Suk Ngo RB Pathology Nasopharyngeal Carcinoma (NPC) occurs as a consequence of multiple molecular events induced by environmental factors and Epstein-Barr virus (EBV) infections. The neoplastic processes may involve alterations of the tumor suppressor genes and oncogenes by genetic damage and interference with the normal cellular functions by the EBV latent gene products. Overexpression of TNF receptor-associated factor 6 (TRAF6) has been reported to suppress orilP activity and loss of EBV from Burkitt's lymphoma cell line. The role of vigilin in cytoplasmic mRNA metabolism has been suggested whereby alterations in mRNA regulation by RNA binding protein have been reported in diverse cancer types. Universiti Malaysia Sarawak, (UNIMAS) 2011 Thesis NonPeerReviewed text en http://ir.unimas.my/id/eprint/13304/1/Chua%20Suk%20Ngo%20ft.pdf Chua, Suk Ngo (2011) Molecular study of selected differentially expressed genes in nasopharyngeal carcinoma. Masters thesis, Faculty of Resources Science & Technology.
institution Universiti Malaysia Sarawak
building Centre for Academic Information Services (CAIS)
collection Institutional Repository
continent Asia
country Malaysia
content_provider Universiti Malaysia Sarawak
content_source UNIMAS Institutional Repository
url_provider http://ir.unimas.my/
language English
topic RB Pathology
spellingShingle RB Pathology
Chua, Suk Ngo
Molecular study of selected differentially expressed genes in nasopharyngeal carcinoma
description Nasopharyngeal Carcinoma (NPC) occurs as a consequence of multiple molecular events induced by environmental factors and Epstein-Barr virus (EBV) infections. The neoplastic processes may involve alterations of the tumor suppressor genes and oncogenes by genetic damage and interference with the normal cellular functions by the EBV latent gene products. Overexpression of TNF receptor-associated factor 6 (TRAF6) has been reported to suppress orilP activity and loss of EBV from Burkitt's lymphoma cell line. The role of vigilin in cytoplasmic mRNA metabolism has been suggested whereby alterations in mRNA regulation by RNA binding protein have been reported in diverse cancer types.
format Thesis
author Chua, Suk Ngo
author_facet Chua, Suk Ngo
author_sort Chua, Suk Ngo
title Molecular study of selected differentially expressed genes in nasopharyngeal carcinoma
title_short Molecular study of selected differentially expressed genes in nasopharyngeal carcinoma
title_full Molecular study of selected differentially expressed genes in nasopharyngeal carcinoma
title_fullStr Molecular study of selected differentially expressed genes in nasopharyngeal carcinoma
title_full_unstemmed Molecular study of selected differentially expressed genes in nasopharyngeal carcinoma
title_sort molecular study of selected differentially expressed genes in nasopharyngeal carcinoma
publisher Universiti Malaysia Sarawak, (UNIMAS)
publishDate 2011
url http://ir.unimas.my/id/eprint/13304/1/Chua%20Suk%20Ngo%20ft.pdf
http://ir.unimas.my/id/eprint/13304/
_version_ 1767209799263453184
score 13.1944895

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