Synthesis, characterization and antibacterial activity of bis thiourea derivatives
A series of bisthiourea derivatives were succesfully synthesized by reaction of benzene-1, 4 dicarbonyl isothiocyanate intermediates and isophthaloyl dichloride, with a series of aromatic amine at ortho, meta and para position. The structure of synthesised compound characterized by infra-red spect...
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Universiti Malaysia Sarawak, (UNIMAS)
2015
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Online Access: | http://ir.unimas.my/id/eprint/11053/9/Synthesis%2C%20Characterization..%28fulltext%29.pdf http://ir.unimas.my/id/eprint/11053/ |
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my.unimas.ir.110532023-06-28T07:04:38Z http://ir.unimas.my/id/eprint/11053/ Synthesis, characterization and antibacterial activity of bis thiourea derivatives Jayakumar, Ponniasalan RV Botanic, Thomsonian, and eclectic medicine A series of bisthiourea derivatives were succesfully synthesized by reaction of benzene-1, 4 dicarbonyl isothiocyanate intermediates and isophthaloyl dichloride, with a series of aromatic amine at ortho, meta and para position. The structure of synthesised compound characterized by infra-red spectroscopy (FTIR), 1H Nuclear magnetic resonances, and 13C Nuclear magnetic resonances. The synthesised compounds were screened for their antibacterial properties using Gram-negative bacteria Escherichia coli (E.coli) by using disc diffusion method. All of synthesized series showed negative results towards antibacterial activity. Universiti Malaysia Sarawak, (UNIMAS) 2015 Final Year Project Report NonPeerReviewed text en http://ir.unimas.my/id/eprint/11053/9/Synthesis%2C%20Characterization..%28fulltext%29.pdf Jayakumar, Ponniasalan (2015) Synthesis, characterization and antibacterial activity of bis thiourea derivatives. [Final Year Project Report] (Unpublished) |
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RV Botanic, Thomsonian, and eclectic medicine Jayakumar, Ponniasalan Synthesis, characterization and antibacterial activity of bis thiourea derivatives |
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A series of bisthiourea derivatives were succesfully synthesized by reaction of benzene-1, 4 dicarbonyl isothiocyanate intermediates and isophthaloyl dichloride, with a series of aromatic amine at ortho, meta and para position. The structure of synthesised compound characterized by infra-red spectroscopy (FTIR), 1H Nuclear magnetic resonances, and 13C Nuclear magnetic resonances. The synthesised compounds were screened for their antibacterial properties using Gram-negative bacteria Escherichia coli (E.coli) by using disc diffusion method. All of synthesized series showed negative results towards antibacterial activity. |
format |
Final Year Project Report |
author |
Jayakumar, Ponniasalan |
author_facet |
Jayakumar, Ponniasalan |
author_sort |
Jayakumar, Ponniasalan |
title |
Synthesis, characterization and antibacterial activity of bis thiourea derivatives |
title_short |
Synthesis, characterization and antibacterial activity of bis thiourea derivatives |
title_full |
Synthesis, characterization and antibacterial activity of bis thiourea derivatives |
title_fullStr |
Synthesis, characterization and antibacterial activity of bis thiourea derivatives |
title_full_unstemmed |
Synthesis, characterization and antibacterial activity of bis thiourea derivatives |
title_sort |
synthesis, characterization and antibacterial activity of bis thiourea derivatives |
publisher |
Universiti Malaysia Sarawak, (UNIMAS) |
publishDate |
2015 |
url |
http://ir.unimas.my/id/eprint/11053/9/Synthesis%2C%20Characterization..%28fulltext%29.pdf http://ir.unimas.my/id/eprint/11053/ |
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1770555374030553088 |
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13.18916 |