Acidified water extraction increases carpaine yield from Carica papaya L. Leaf

• Main Authors: Sim, Tze Tak, Nor Hisam, Zamakshshari, Mohamad Fhaizal, Mohamad Bukhori, Eswaran, Madiahlagan, Rafeah, Wahi, Lawrence, Anchah
• Format: Article
• Language: English
• Published: Malaysian Society for Molecular Biology and Biotechnology 2024
• Subjects: Q Science (General); QD Chemistry; QK Botany; R Medicine (General); RM Therapeutics. Pharmacology
• Online Access: http://ir.unimas.my/id/eprint/47199/1/24-Tak-et-al.pdf; http://ir.unimas.my/id/eprint/47199/; http://www.msmbb.my/index.php/publication; https://doi.org/10.35118/apjmbb.2024.032.4.24

Carica papaya leaves have been traditionally used in various medicinal applications. The major alkaloid, carpaine, is widely studied for its anti-thrombocytopenic activity. However, extraction of carpaine from Carica papaya leaves remains challenging, and the existing methods may not yield high amou...