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Development of nanogap based dielectric biosensor for label-free medical diagnostic analytical measurement

Malaysian Technical Universities Conference on Engineering and Technology (MUCEET) 2009 organized by Universiti Malaysia Pahang in collaboration with Universiti Tun Hussein Onn Malaysia, Universiti Teknikal Malaysia Melaka & Universiti Malaysia Perlis, 20th - 22nd June 2009 at MS Garden Hotel, K...

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Main Authors: A., Mat Taib, Uda, Hashim, Prof. Dr., N. A., Yusof, Th. S., Dhahi
Format: Working Paper
Language:English
Published: Universiti Malaysia Pahang 2010
Subjects:
Nanogap sensing
Dielectric biosensor
Label-free detection
Silicon nanostructure
Bio-molecule immobilization
Hybridization
MUCEET 2009
Malaysian Technical Universities Conference on Engineering and Technology 2009
Online Access:http://dspace.unimap.edu.my/xmlui/handle/123456789/8511
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spelling my.unimap-85112010-08-06T10:01:45Z Development of nanogap based dielectric biosensor for label-free medical diagnostic analytical measurement A., Mat Taib Uda, Hashim, Prof. Dr. N. A., Yusof Th. S., Dhahi Nanogap sensing Dielectric biosensor Label-free detection Silicon nanostructure Bio-molecule immobilization Hybridization MUCEET 2009 Malaysian Technical Universities Conference on Engineering and Technology 2009 Malaysian Technical Universities Conference on Engineering and Technology (MUCEET) 2009 organized by Universiti Malaysia Pahang in collaboration with Universiti Tun Hussein Onn Malaysia, Universiti Teknikal Malaysia Melaka & Universiti Malaysia Perlis, 20th - 22nd June 2009 at MS Garden Hotel, Kuantan, Pahang, Malaysia. Biosensor with electrode distances 75 nm and highly sensitive and selective is proposed in this research. The target application is the label-free detection of bio-molecular interaction for medical diagnostic analytical measurement. The fabrication process of the biosensor is based on conventional photolithography, e-beam evaporation and wet etching process. Sacrificial layer technique is applied in this research to form nanometer gap size between bottom and top electrode. Gold was chosen because of its properties that inert to atmosphere conditions and resistance to saline solution for bio-molecules immobilization and hybridization. For morphological and physical characterization, SEM, TEM and AFM are will be used while for electrical characterization, SPA and IV-CV system is used to determine the conductivity, capacitance and resistivity of the device. DNA is used as a sample for testing and the DNA extraction and preparation is done prior to immobilization and hybridization. 2010-08-06T10:01:45Z 2010-08-06T10:01:45Z 2009-06-20 Working Paper p.1-5 http://hdl.handle.net/123456789/8511 en Proceedings of the Malaysian Technical Universities Conference on Engineering and Technology (MUCEET) 2009 Universiti Malaysia Pahang
institution Universiti Malaysia Perlis
building UniMAP Library
collection Institutional Repository
continent Asia
country Malaysia
content_provider Universiti Malaysia Perlis
content_source UniMAP Library Digital Repository
url_provider http://dspace.unimap.edu.my/
language English
topic Nanogap sensing
Dielectric biosensor
Label-free detection
Silicon nanostructure
Bio-molecule immobilization
Hybridization
MUCEET 2009
Malaysian Technical Universities Conference on Engineering and Technology 2009
spellingShingle Nanogap sensing
Dielectric biosensor
Label-free detection
Silicon nanostructure
Bio-molecule immobilization
Hybridization
MUCEET 2009
Malaysian Technical Universities Conference on Engineering and Technology 2009
A., Mat Taib
Uda, Hashim, Prof. Dr.
N. A., Yusof
Th. S., Dhahi
Development of nanogap based dielectric biosensor for label-free medical diagnostic analytical measurement
description Malaysian Technical Universities Conference on Engineering and Technology (MUCEET) 2009 organized by Universiti Malaysia Pahang in collaboration with Universiti Tun Hussein Onn Malaysia, Universiti Teknikal Malaysia Melaka & Universiti Malaysia Perlis, 20th - 22nd June 2009 at MS Garden Hotel, Kuantan, Pahang, Malaysia.
format Working Paper
author A., Mat Taib
Uda, Hashim, Prof. Dr.
N. A., Yusof
Th. S., Dhahi
author_facet A., Mat Taib
Uda, Hashim, Prof. Dr.
N. A., Yusof
Th. S., Dhahi
author_sort A., Mat Taib
title Development of nanogap based dielectric biosensor for label-free medical diagnostic analytical measurement
title_short Development of nanogap based dielectric biosensor for label-free medical diagnostic analytical measurement
title_full Development of nanogap based dielectric biosensor for label-free medical diagnostic analytical measurement
title_fullStr Development of nanogap based dielectric biosensor for label-free medical diagnostic analytical measurement
title_full_unstemmed Development of nanogap based dielectric biosensor for label-free medical diagnostic analytical measurement
title_sort development of nanogap based dielectric biosensor for label-free medical diagnostic analytical measurement
publisher Universiti Malaysia Pahang
publishDate 2010
url http://dspace.unimap.edu.my/xmlui/handle/123456789/8511
_version_ 1643789198987100160
score 13.214268

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