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Integrated optical Mach-Zehnder interferometer for biosensor application

Master of Science in Microelectronic Engineering

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Bibliographic Details
Main Author: Khor, Kang Nan
Other Authors: Mukhzeer, Mohamad Shahimin, Dr.
Format: Thesis
Language:English
Published: Universiti Malaysia Perlis (UniMAP) 2015
Subjects:
Interferometers
Integrated optics
Biosensors
Point-of-care testing
Dengue
Dengue Biosensor
Online Access:http://dspace.unimap.edu.my:80/xmlui/handle/123456789/77056
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spelling my.unimap-770562022-11-17T01:35:39Z Integrated optical Mach-Zehnder interferometer for biosensor application Khor, Kang Nan Mukhzeer, Mohamad Shahimin, Dr. Interferometers Integrated optics Biosensors Point-of-care testing Dengue Dengue Biosensor Master of Science in Microelectronic Engineering Dengue is an emerging global health problem affecting over half the world’s population. With the rapid pace of population growth and climate change, the population at risk of dengue has reached the figure of 2.5-3.0 billions, approximately 40% of the world’s population. Malaysia, a dengue hyperendemic country located near the equator, is one of the most affected countries by dengue in Western-Pacific region. The national target for the incidence rate of DF/DHF cases, 50 cases per 100,000 populations, has long been exceeded since 2005 until now. Rapid diagnostic test is in great demand ever since, however the current RDT is not sufficient as an effective passive surveillance system due to the high cost and lack of accuracy. Hence, this study aimed to develop a dengue RDT that is not only have the characteristics of point-ofcare (POC) diagnostic but also suits the criteria needed to achieve a large scale disease surveillance in most developing countries where resources are limited. Label-free optical biosensor had been proposed to realized an ideal surveillance RDT. The design of integrated optic Mach-Zehnder Interferometer (IO-MZI) biosensor had been carried out based on the simulation and fabrication method. Simulation of IO-MZI was carried out by using three-dimensional finite difference beam propagation method with the aim of sensitivity and detection limit optimization. OptiBPM software is selected because it is user-friendly and it allows three-dimensional simulation which is needed in this research. 2015 2022-11-17T01:34:10Z 2022-11-17T01:34:10Z Thesis http://dspace.unimap.edu.my:80/xmlui/handle/123456789/77056 en Universiti Malaysia Perlis (UniMAP) Universiti Malaysia Perlis (UniMAP) School of Microelectronic Engineering
institution Universiti Malaysia Perlis
building UniMAP Library
collection Institutional Repository
continent Asia
country Malaysia
content_provider Universiti Malaysia Perlis
content_source UniMAP Library Digital Repository
url_provider http://dspace.unimap.edu.my/
language English
topic Interferometers
Integrated optics
Biosensors
Point-of-care testing
Dengue
Dengue Biosensor
spellingShingle Interferometers
Integrated optics
Biosensors
Point-of-care testing
Dengue
Dengue Biosensor
Khor, Kang Nan
Integrated optical Mach-Zehnder interferometer for biosensor application
description Master of Science in Microelectronic Engineering
author2 Mukhzeer, Mohamad Shahimin, Dr.
author_facet Mukhzeer, Mohamad Shahimin, Dr.
Khor, Kang Nan
format Thesis
author Khor, Kang Nan
author_sort Khor, Kang Nan
title Integrated optical Mach-Zehnder interferometer for biosensor application
title_short Integrated optical Mach-Zehnder interferometer for biosensor application
title_full Integrated optical Mach-Zehnder interferometer for biosensor application
title_fullStr Integrated optical Mach-Zehnder interferometer for biosensor application
title_full_unstemmed Integrated optical Mach-Zehnder interferometer for biosensor application
title_sort integrated optical mach-zehnder interferometer for biosensor application
publisher Universiti Malaysia Perlis (UniMAP)
publishDate 2015
url http://dspace.unimap.edu.my:80/xmlui/handle/123456789/77056
_version_ 1751537837878018048
score 13.214268

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