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Design and Fabrication of Biodegradable Microneedle Using 3D Rapid Prototyping Printer

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Main Authors: Nur Hazwani Azyan, Mansor, Marni Azira, Markom, Erdy Sulino, Mohd Muslim Tan, Abdul Hamid, Adom
Other Authors: marni@unimap.edu.my
Format: Article
Language:English
Published: IOP Publishing 2020
Subjects:
Microneedle
Transdermal drug delivery (TDD)
Biodegradable microneedle
Online Access:http://dspace.unimap.edu.my:80/xmlui/handle/123456789/69031
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spelling my.unimap-690312020-12-16T08:34:03Z Design and Fabrication of Biodegradable Microneedle Using 3D Rapid Prototyping Printer Nur Hazwani Azyan, Mansor Marni Azira, Markom Erdy Sulino, Mohd Muslim Tan Abdul Hamid, Adom marni@unimap.edu.my Microneedle Transdermal drug delivery (TDD) Biodegradable microneedle Link to publisher's homepage at https://iopscience.iop.org/ Microneedle is known as transdermal drug delivery (TDD) devices that uses to deliver biological fluid into veins and needle that use to tear skin to collect blood sample. It involves with various parameters and designs. This device gain attention as its benefit can eliminate pain and more convenient compared to intravenous injection due to its micron size. Typically, microneedle is fabricated using MEMS technology. However, this technology requires few processes such as deposition, etching and moulding, as well as consume much times. This paper presents a work of design and fabrication of solid microneedle using 3D rapid prototype printing. A few types of microneedles are designed and they are analysed in terms of stress and force characteristics. Also, it will study the ability of a few materials to withstand stress while force exerted on it. The selected materials are polyvinyl alcohol (PVA), polylactic acid (PLA), polyester resin and acrylonitrile butadiene styrene (ABS). The results show that PVA has the highest ability to withstand force compared other materials. As conclusion, the design and fabrication of microneedle using 3D rapid prototyping printer is succeed using PVA material and real post-analysis can be conducted to test the capability for medical practice. 2020-12-16T08:34:03Z 2020-12-16T08:34:03Z 2019 Article Journal of Physics: Conference Series, vol.1372, 2019, 6 pages 1742-6588 (print) 1742-6596 (online) http://dspace.unimap.edu.my:80/xmlui/handle/123456789/69031 https://iopscience.iop.org/issue/1742-6596/1372/1 en International Conference on Biomedical Engineering (ICoBE); IOP Publishing
institution Universiti Malaysia Perlis
building UniMAP Library
collection Institutional Repository
continent Asia
country Malaysia
content_provider Universiti Malaysia Perlis
content_source UniMAP Library Digital Repository
url_provider http://dspace.unimap.edu.my/
language English
topic Microneedle
Transdermal drug delivery (TDD)
Biodegradable microneedle
spellingShingle Microneedle
Transdermal drug delivery (TDD)
Biodegradable microneedle
Nur Hazwani Azyan, Mansor
Marni Azira, Markom
Erdy Sulino, Mohd Muslim Tan
Abdul Hamid, Adom
Design and Fabrication of Biodegradable Microneedle Using 3D Rapid Prototyping Printer
description Link to publisher's homepage at https://iopscience.iop.org/
author2 marni@unimap.edu.my
author_facet marni@unimap.edu.my
Nur Hazwani Azyan, Mansor
Marni Azira, Markom
Erdy Sulino, Mohd Muslim Tan
Abdul Hamid, Adom
format Article
author Nur Hazwani Azyan, Mansor
Marni Azira, Markom
Erdy Sulino, Mohd Muslim Tan
Abdul Hamid, Adom
author_sort Nur Hazwani Azyan, Mansor
title Design and Fabrication of Biodegradable Microneedle Using 3D Rapid Prototyping Printer
title_short Design and Fabrication of Biodegradable Microneedle Using 3D Rapid Prototyping Printer
title_full Design and Fabrication of Biodegradable Microneedle Using 3D Rapid Prototyping Printer
title_fullStr Design and Fabrication of Biodegradable Microneedle Using 3D Rapid Prototyping Printer
title_full_unstemmed Design and Fabrication of Biodegradable Microneedle Using 3D Rapid Prototyping Printer
title_sort design and fabrication of biodegradable microneedle using 3d rapid prototyping printer
publisher IOP Publishing
publishDate 2020
url http://dspace.unimap.edu.my:80/xmlui/handle/123456789/69031
_version_ 1698698546278039552
score 13.214268

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