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Human health risk assessment of chlorinated disinfection by-products in drinking water using a probabilistic approach

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Main Authors: Nasrul, Hamidin, Yu, Qiming Jimmy, Connell, Des William
Other Authors: nasrulhamidin@unimap.edu.my
Format: Article
Language:English
Published: Elsevier Limited 2016
Subjects:
Disinfection by-products (DBPs)
Drinking water
Health risk assessment
Probabilistic technique
Online Access:http://dspace.unimap.edu.my:80/xmlui/handle/123456789/41134
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spelling my.unimap-411342016-03-14T02:06:53Z Human health risk assessment of chlorinated disinfection by-products in drinking water using a probabilistic approach Nasrul, Hamidin Yu, Qiming Jimmy Connell, Des William nasrulhamidin@unimap.edu.my Disinfection by-products (DBPs) Drinking water Health risk assessment Probabilistic technique Link to publisher's homepage at https://www.elsevier.com The presence of chlorinated disinfection by-products (DBPs) in drinking water is a public health issue, due to their possible adverse health effects on humans. To gauge the risk of chlorinated DBPs on human health, a risk assessment of chloroform (trichloromethane (TCM)), bromodichloromethane (BDCM), dibromochloromethane (DBCM), bromoform (tribromomethane (TBM)), dichloroacetic acid (DCAA) and trichloroacetic acid (TCAA) in drinking water was carried out using probabilistic techniques. Literature data on exposure concentrations from more than 15 different countries and adverse health effects on test animals as well as human epidemiological studies were used. The risk assessment showed no overlap between the highest human exposure dose (EXPD) and the lowest human equivalent dose (HED) from animal test data, for TCM, BDCM, DBCM, TBM, DCAA and TCAA. All the HED values were approximately 104-10 5 times higher than the 95th percentiles of EXPD. However, from the human epidemiology data, there was a positive overlap between the highest EXPD and the lifetime average daily doses (LADDH) for TCM, BDCM, DCAA and TCAA. This suggests that there are possible adverse health risks such as a small increased incidence of cancers in males and developmental effects on infants. However, the epidemiological data comprised several risk factors and exposure classification levels which may affect the overall results. 2016-03-14T02:06:53Z 2016-03-14T02:06:53Z 2008-07 Article Water Research, vol.42 (13), 2008, pages 3263-3274 0043-1354 1879-2448 (online) http://dspace.unimap.edu.my:80/xmlui/handle/123456789/41134 en Elsevier Limited
institution Universiti Malaysia Perlis
building UniMAP Library
collection Institutional Repository
continent Asia
country Malaysia
content_provider Universiti Malaysia Perlis
content_source UniMAP Library Digital Repository
url_provider http://dspace.unimap.edu.my/
language English
topic Disinfection by-products (DBPs)
Drinking water
Health risk assessment
Probabilistic technique
spellingShingle Disinfection by-products (DBPs)
Drinking water
Health risk assessment
Probabilistic technique
Nasrul, Hamidin
Yu, Qiming Jimmy
Connell, Des William
Human health risk assessment of chlorinated disinfection by-products in drinking water using a probabilistic approach
description Link to publisher's homepage at https://www.elsevier.com
author2 nasrulhamidin@unimap.edu.my
author_facet nasrulhamidin@unimap.edu.my
Nasrul, Hamidin
Yu, Qiming Jimmy
Connell, Des William
format Article
author Nasrul, Hamidin
Yu, Qiming Jimmy
Connell, Des William
author_sort Nasrul, Hamidin
title Human health risk assessment of chlorinated disinfection by-products in drinking water using a probabilistic approach
title_short Human health risk assessment of chlorinated disinfection by-products in drinking water using a probabilistic approach
title_full Human health risk assessment of chlorinated disinfection by-products in drinking water using a probabilistic approach
title_fullStr Human health risk assessment of chlorinated disinfection by-products in drinking water using a probabilistic approach
title_full_unstemmed Human health risk assessment of chlorinated disinfection by-products in drinking water using a probabilistic approach
title_sort human health risk assessment of chlorinated disinfection by-products in drinking water using a probabilistic approach
publisher Elsevier Limited
publishDate 2016
url http://dspace.unimap.edu.my:80/xmlui/handle/123456789/41134
_version_ 1643799590313394176
score 13.222552

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