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Advances in biosensors: Principle, architecture and applications

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Main Authors: Veeradasan, Perumal, Uda, Hashim, Prof. Dr.
Other Authors: veeradasan@hotmail.my
Format: Article
Language:English
Published: Elsevier 2014
Subjects:
Transducer
Bioreceptor
Enzyme
Antibody
DNA
Pathology
Diagnosis
Online Access:http://dspace.unimap.edu.my:80/dspace/handle/123456789/35103
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spelling my.unimap-351032014-06-05T03:33:13Z Advances in biosensors: Principle, architecture and applications Veeradasan, Perumal Uda, Hashim, Prof. Dr. veeradasan@hotmail.my Transducer Bioreceptor Enzyme Antibody DNA Pathology Diagnosis Link to publisher's homepage at http://www.journals.elsevier.com The ability to detect pathogenic and physiologically relevant molecules in the body with high sensitivity and specificity offers a powerful opportunity in the early diagnosis and treatment of diseases. Early detection and diagnosis can be used to greatly reduce the cost of patient care associated with the advanced stages of many diseases. However, despite their widespread clinical use, these techniques have a number of potential limitations. For example, a number of diagnostic devices have slow response times and are burdensome to patients. Furthermore, these assays are expensive and cost the health care industry billions of dollars every year. Therefore, there is a need to develop more efficient and reliable sensing and detection technologies. A biosensor is commonly defined as an analytical device that uses a biological recognition system to target molecules or macromolecules. Biosensors can be coupled to a physiochemical transducer that converts this recognition into a detectable output signal. Typically biosensors are comprised of three components: (1) the detector, which identifies the stimulus; (2) the transducer, which converts this stimulus to a useful output; and (3) the signal processing system, which involves amplification and display of the output in an appropriate format. The goal of this combination is to utilize the high sensitivity and selectivity of biological sensing for analytical purposes in various fields of research and technology. We review here some of the main advances in this field over the past few years, explore the application prospects, and discuss the issues, approaches, and challenges, with the aim of stimulating a broader interest in developing biosensors and improving their applications in medical diagnosis. 2014-06-05T03:33:13Z 2014-06-05T03:33:13Z 2014-01 Article Journal of Applied Biomedicine, vol.12 (1), 2014, pages 1–15 1214-021X (print) 1214-0287 (online) http://dspace.unimap.edu.my:80/dspace/handle/123456789/35103 http://www.sciencedirect.com/science/article/pii/S1214021X13000082 en Elsevier
institution Universiti Malaysia Perlis
building UniMAP Library
collection Institutional Repository
continent Asia
country Malaysia
content_provider Universiti Malaysia Perlis
content_source UniMAP Library Digital Repository
url_provider http://dspace.unimap.edu.my/
language English
topic Transducer
Bioreceptor
Enzyme
Antibody
DNA
Pathology
Diagnosis
spellingShingle Transducer
Bioreceptor
Enzyme
Antibody
DNA
Pathology
Diagnosis
Veeradasan, Perumal
Uda, Hashim, Prof. Dr.
Advances in biosensors: Principle, architecture and applications
description Link to publisher's homepage at http://www.journals.elsevier.com
author2 veeradasan@hotmail.my
author_facet veeradasan@hotmail.my
Veeradasan, Perumal
Uda, Hashim, Prof. Dr.
format Article
author Veeradasan, Perumal
Uda, Hashim, Prof. Dr.
author_sort Veeradasan, Perumal
title Advances in biosensors: Principle, architecture and applications
title_short Advances in biosensors: Principle, architecture and applications
title_full Advances in biosensors: Principle, architecture and applications
title_fullStr Advances in biosensors: Principle, architecture and applications
title_full_unstemmed Advances in biosensors: Principle, architecture and applications
title_sort advances in biosensors: principle, architecture and applications
publisher Elsevier
publishDate 2014
url http://dspace.unimap.edu.my:80/dspace/handle/123456789/35103
_version_ 1643797706393518080
score 13.18916

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