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The study of morphological structure, phase structure and molecular structure of collagen-PEO 600K blends for tissue engineering application

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Format: Article
Language:English
Published: Science Publications 2014
Subjects:
SEM
XRD
FTIR
PEO
Collagen
Tissue scaffold
Online Access:http://dspace.unimap.edu.my:80/dspace/handle/123456789/34824
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spelling my.unimap-348242014-05-28T06:33:33Z The study of morphological structure, phase structure and molecular structure of collagen-PEO 600K blends for tissue engineering application SEM XRD FTIR PEO Collagen Tissue scaffold Link to publisher's homepage at http://thescipub.com/ A new material which is collagen/ poly (ethylene oxide) (PEO) blend was developed to determine its possibility as a promising material for tissue scaffold. PEO with average molecular weight of 600,000 and collagen originated from calf skin were dispersed in 0.1 M acetic acid to prepare a concentration of 1 wt% for PEO and 0.15 wt% for collagen. The collagen-PEO600K blend film was then obtained by solution casting method. SEM results shown that by having certain ratio of collagen and PEO, the membrane began to developed porous structures which are possible to assist tissue attachment on the scaffold. The X-ray diffractograms demonstrate PEO 600K influences on the blend thus enhancing crystallinity of collagen. The Infra red spectrum shows intermolecular interactions of collagen and PEO which alter the collagen structure thus explained the membrane morphological changes. Therefore, we concluded that the phase structure and also the molecular structure of the blend are crucial to produce desirable morphological structure of the membrane which is required for a reliable tissue scaffold. 2014-05-28T06:32:36Z 2014-05-28T06:32:36Z 2006 Article American Journal of Biochemistry and Biotechnology, vol. 2(4), 2006, pages 175-179 1553-3468 http://thescipub.com/abstract/10.3844/ajbbsp.2006.175.179 http://dspace.unimap.edu.my:80/dspace/handle/123456789/34824 10.3844/ajbbsp.2006.175.179 en Science Publications
institution Universiti Malaysia Perlis
building UniMAP Library
collection Institutional Repository
continent Asia
country Malaysia
content_provider Universiti Malaysia Perlis
content_source UniMAP Library Digital Repository
url_provider http://dspace.unimap.edu.my/
language English
topic SEM
XRD
FTIR
PEO
Collagen
Tissue scaffold
spellingShingle SEM
XRD
FTIR
PEO
Collagen
Tissue scaffold
The study of morphological structure, phase structure and molecular structure of collagen-PEO 600K blends for tissue engineering application
description Link to publisher's homepage at http://thescipub.com/
format Article
title The study of morphological structure, phase structure and molecular structure of collagen-PEO 600K blends for tissue engineering application
title_short The study of morphological structure, phase structure and molecular structure of collagen-PEO 600K blends for tissue engineering application
title_full The study of morphological structure, phase structure and molecular structure of collagen-PEO 600K blends for tissue engineering application
title_fullStr The study of morphological structure, phase structure and molecular structure of collagen-PEO 600K blends for tissue engineering application
title_full_unstemmed The study of morphological structure, phase structure and molecular structure of collagen-PEO 600K blends for tissue engineering application
title_sort study of morphological structure, phase structure and molecular structure of collagen-peo 600k blends for tissue engineering application
publisher Science Publications
publishDate 2014
url http://dspace.unimap.edu.my:80/dspace/handle/123456789/34824
_version_ 1643797609739976704
score 13.222552

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