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Design and fabrication of PDMS microchamber for fast reaction assays in biosensing application.

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Main Authors: Tijjani Adam, Shuwa, Uda, Hashim, Prof. Dr., A.Wesam, Al-Mufti
Other Authors: tijjaniadam@yahoo.com.my
Format: Article
Language:English
Published: Trans Tech Publications 2014
Subjects:
Capillary
Comsol multiphysics
Fabrication
Microchannel
Microfluidics
PDMS
Soft lithoraphy
Online Access:http://dspace.unimap.edu.my:80/dspace/handle/123456789/32429
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spelling my.unimap-324292014-03-09T02:55:28Z Design and fabrication of PDMS microchamber for fast reaction assays in biosensing application. Tijjani Adam, Shuwa Uda, Hashim, Prof. Dr. A.Wesam, Al-Mufti tijjaniadam@yahoo.com.my uda@unimap.edu.my mohamenw@gmail.com Capillary Comsol multiphysics Fabrication Microchannel Microfluidics PDMS Soft lithoraphy Link to publisher's homepage at http://www.ttp.net/ A simple design of a microchamber for use in reacting assays with limited sample availability has been proposed, analyzed using COMSOL 3.5 Multiphysics simulation and fabricated using soft-lithography technique. The design is based on differential pressure drop flow using capillary effect concept which has facilitated a number of interesting flow phenomena in micro-domains. For an average pressure drop of about 100/m in the setup, flow rates of bout 0.5 to 0.8 μl/s were obtained. The component a microchamber, three designs were tested (50, 70, 90 microns in width) to give a continuous open circuit flow. The system was designed and fabricated for continuous flow across sensing element where there is a requirement for low residence time due to fast reaction/diffusion rates.Also in this paper, is a sensitive and selective, also rapid, reliable, cost-effective, and suitable for in situ analysis polymer biosensor for new bio molecular approach for cancer and cancer related diseases detection at the early stage is demonstrated. 2014-03-09T02:55:28Z 2014-03-09T02:55:28Z 2013 Article Advanced Materials Research, vol. 795, 2013, pages 329-333 978-303785811-0 10226680 http://www.scientific.net/AMR.795.329 http://dspace.unimap.edu.my:80/dspace/handle/123456789/32429 en Trans Tech Publications
institution Universiti Malaysia Perlis
building UniMAP Library
collection Institutional Repository
continent Asia
country Malaysia
content_provider Universiti Malaysia Perlis
content_source UniMAP Library Digital Repository
url_provider http://dspace.unimap.edu.my/
language English
topic Capillary
Comsol multiphysics
Fabrication
Microchannel
Microfluidics
PDMS
Soft lithoraphy
spellingShingle Capillary
Comsol multiphysics
Fabrication
Microchannel
Microfluidics
PDMS
Soft lithoraphy
Tijjani Adam, Shuwa
Uda, Hashim, Prof. Dr.
A.Wesam, Al-Mufti
Design and fabrication of PDMS microchamber for fast reaction assays in biosensing application.
description Link to publisher's homepage at http://www.ttp.net/
author2 tijjaniadam@yahoo.com.my
author_facet tijjaniadam@yahoo.com.my
Tijjani Adam, Shuwa
Uda, Hashim, Prof. Dr.
A.Wesam, Al-Mufti
format Article
author Tijjani Adam, Shuwa
Uda, Hashim, Prof. Dr.
A.Wesam, Al-Mufti
author_sort Tijjani Adam, Shuwa
title Design and fabrication of PDMS microchamber for fast reaction assays in biosensing application.
title_short Design and fabrication of PDMS microchamber for fast reaction assays in biosensing application.
title_full Design and fabrication of PDMS microchamber for fast reaction assays in biosensing application.
title_fullStr Design and fabrication of PDMS microchamber for fast reaction assays in biosensing application.
title_full_unstemmed Design and fabrication of PDMS microchamber for fast reaction assays in biosensing application.
title_sort design and fabrication of pdms microchamber for fast reaction assays in biosensing application.
publisher Trans Tech Publications
publishDate 2014
url http://dspace.unimap.edu.my:80/dspace/handle/123456789/32429
_version_ 1643796899850878976
score 13.222552

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