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Using additive manufactured tooling in the fabrication of poly (L-lactide-co-glycolide) implants

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Bibliographic Details
Main Authors: Shah Fenner Khan, Mohamad Khan, Dalgarno, Kenneth W., German, Matthew J.
Other Authors: shahfener@unimap.edu.my
Format: Working Paper
Language:English
Published: Taylor & Francis Group, London. 2014
Subjects:
Fabrication
Bone structure
Poly (L-lactide-co-glycolide) (PLGA)
Geometrical shapes
Tissue restoration
Online Access:http://dspace.unimap.edu.my:80/dspace/handle/123456789/32078
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spelling my.unimap-320782014-02-21T07:59:58Z Using additive manufactured tooling in the fabrication of poly (L-lactide-co-glycolide) implants Shah Fenner Khan, Mohamad Khan Dalgarno, Kenneth W. German, Matthew J. shahfener@unimap.edu.my Fabrication Bone structure Poly (L-lactide-co-glycolide) (PLGA) Geometrical shapes Tissue restoration Link to publisher's homepage at http://www.crcpress.com/ Rectification of defective bone structures due to trauma or deformation has benefited from the introduction of mostly rigid metal prostheses. However, the high stiffness of metal implants can cause stress shielding in bone restoration. In addition a second operation is required for the removal of the metal implants, screws, plates, and rods once the bone has healed. This paper discusses an adaptable solution where a customised implant is defined which is secured by adhesion and resorbable to enable tissue restoration without a second operation. This paper describes research on methods of creating customised structures from poly (L-lactide-co-glycolide) (PLGA). An existing 3D mandible model in stereolithography file format was used as the basis for this research which a rapid tooling approach is used to create a mould for sintering PLGA particles. The tooling was developed through a stl file of a mandible being imported into a NURBS-based CAD modeller. The modeller was used to create a 3D solid patch model for use as an implantable fracture fixation component. Based on the 3D patch, the tooling was designed and then fabricated by using Stereolitography. Granules of PLGA were placed inside the mould and heated under low pressure to produce the scaffolds with three different formulation of PLGA used in this study. Consolidation of the PLGA occurred under constant pressure with a sintering temperature of 73°C for 2.5hours. Mechanical testing was performed on samples and the results were comparable with conventional processing of PLGA. The geometrical shape of the fabricated PLGA implant resembles the desired fixation component and fits accurately to the fracture site. This work demonstrates that this approach is a viable route in fabricating customised PLGA structures for orthopaedic surgery. 2014-02-21T07:58:51Z 2014-02-21T07:58:51Z 2011-09-28 Working Paper p. 437-441 978-041568418-7 http://www.crcnetbase.com/doi/abs/10.1201/b11341-70 http://dspace.unimap.edu.my:80/dspace/handle/123456789/32078 en Proceedings of the 5th International Conference on Advanced Research and Rapid Prototyping; Taylor & Francis Group, London.
institution Universiti Malaysia Perlis
building UniMAP Library
collection Institutional Repository
continent Asia
country Malaysia
content_provider Universiti Malaysia Perlis
content_source UniMAP Library Digital Repository
url_provider http://dspace.unimap.edu.my/
language English
topic Fabrication
Bone structure
Poly (L-lactide-co-glycolide) (PLGA)
Geometrical shapes
Tissue restoration
spellingShingle Fabrication
Bone structure
Poly (L-lactide-co-glycolide) (PLGA)
Geometrical shapes
Tissue restoration
Shah Fenner Khan, Mohamad Khan
Dalgarno, Kenneth W.
German, Matthew J.
Using additive manufactured tooling in the fabrication of poly (L-lactide-co-glycolide) implants
description Link to publisher's homepage at http://www.crcpress.com/
author2 shahfener@unimap.edu.my
author_facet shahfener@unimap.edu.my
Shah Fenner Khan, Mohamad Khan
Dalgarno, Kenneth W.
German, Matthew J.
format Working Paper
author Shah Fenner Khan, Mohamad Khan
Dalgarno, Kenneth W.
German, Matthew J.
author_sort Shah Fenner Khan, Mohamad Khan
title Using additive manufactured tooling in the fabrication of poly (L-lactide-co-glycolide) implants
title_short Using additive manufactured tooling in the fabrication of poly (L-lactide-co-glycolide) implants
title_full Using additive manufactured tooling in the fabrication of poly (L-lactide-co-glycolide) implants
title_fullStr Using additive manufactured tooling in the fabrication of poly (L-lactide-co-glycolide) implants
title_full_unstemmed Using additive manufactured tooling in the fabrication of poly (L-lactide-co-glycolide) implants
title_sort using additive manufactured tooling in the fabrication of poly (l-lactide-co-glycolide) implants
publisher Taylor & Francis Group, London.
publishDate 2014
url http://dspace.unimap.edu.my:80/dspace/handle/123456789/32078
_version_ 1643796766238179328
score 13.18916

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