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Effects of irradiation sterilisation on medical grade poly (ether-block-amide)

The 2nd International Malaysia-Ireland Joint Symposium on Engineering, Science and Business 2012 (IMiEJS2012) jointly organized by Universiti Malaysia Perlis and Athlone Institute of Technology in collaboration with The Ministry of Higher Education (MOHE) Malaysia, Education Malaysia and Malaysia Po...

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Main Author: Murray, Kieran
Format: Other
Language:English
Published: Universiti Malaysia Perlis (UniMAP) 2013
Subjects:
Irradiation sterilisation
Poly (ether block amide) (PEBA)
Thermoplastic elastomers (TPE)
Gamma ray process
Electron beam process
Online Access:http://dspace.unimap.edu.my/xmlui/handle/123456789/30832
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spelling my.unimap-308322013-12-24T12:44:20Z Effects of irradiation sterilisation on medical grade poly (ether-block-amide) Murray, Kieran Irradiation sterilisation Poly (ether block amide) (PEBA) Thermoplastic elastomers (TPE) Gamma ray process Electron beam process The 2nd International Malaysia-Ireland Joint Symposium on Engineering, Science and Business 2012 (IMiEJS2012) jointly organized by Universiti Malaysia Perlis and Athlone Institute of Technology in collaboration with The Ministry of Higher Education (MOHE) Malaysia, Education Malaysia and Malaysia Postgraduates Student Association Ireland (MyPSI), 18th - 19th June 2012 at Putra World Trade Center (PWTC), Kuala Lumpur, Malaysia Poly (ether block amide) (PEBA) is a family of copolymers which consists of polyamide hard segments and polyether soft segments in the polymer chains. These are thermoplastic elastomers (TPE) which are sold under Arkema’s trade name PEBAX®. They are mainly used in the medical device industry as they offer valuable properties such as elasticity and thermal stability at body temperatures. Its applications range from catheter bodies to angioplasty balloons. For medical device usage, it is of vital importance that the material properties are not deteriorated by sterilisation using ionising irradiation techniques. During radiation exposure, polymers usually undergo simultaneous scission and crosslinking but one generally predominates over the other. The objective of this study was to quantify the effects of electron beam (combined 10/12MeV unit, 30KW) and gamma ray processing on PEBAX material through a diverse array of characterisation techniques. Mechanical testing revealed that the tensile strength and the percentage elongation at break of PEBAX reduced dramatically from 25kGy to 200kGy. This was perhaps related to branching and chain scissioning occurring simultaneously. Branching can limit the packing of polymer chains and lead to the formation of free volume in the material, therefore causing a reduction in the tensile strength and elongation at break. Gamma irradiation resulted in further modifications to the mechanical properties of PEBAX in contrast to electron beam irradiation. Both processes lead to an extreme decrease in the melt flow index which was perhaps as a result of branching / crosslinking. Dynamic frequencies sweeps revealed that the storage modulus increased in the low frequency regime for the gamma irradiated samples while the electron beam irradiated samples remained unchanged. It was observed by SEM that the surface morphology of the non-irradiated (0kGy) sample contained a homogeneous pattern which was much smoother than that of the electron beam irradiated (200kGy) sample. XRD demonstrated slight alteration to the peak intensities signifying a slight change in the polymer matrix. Overall, chain scission and branching were the key modification processes involved which occurred simultaneously. However, it was evident from the results obtained that chain branching/crosslinking was the predominant phenomena particularly at high irradiation dose rates. In addition, this study proved that the gamma ray process was more detrimental on the PEBAX material in contrast to the electron beam process 2013-12-24T12:44:19Z 2013-12-24T12:44:19Z 2012-06-18 Other p. 1278 978-967-5760-11-2 http://hdl.handle.net/123456789/30832 en The 2nd International Malaysia-Ireland Joint Symposium on Engineering, Science and Business 2012 (IMiEJS2012); Universiti Malaysia Perlis (UniMAP)
institution Universiti Malaysia Perlis
building UniMAP Library
collection Institutional Repository
continent Asia
country Malaysia
content_provider Universiti Malaysia Perlis
content_source UniMAP Library Digital Repository
url_provider http://dspace.unimap.edu.my/
language English
topic Irradiation sterilisation
Poly (ether block amide) (PEBA)
Thermoplastic elastomers (TPE)
Gamma ray process
Electron beam process
spellingShingle Irradiation sterilisation
Poly (ether block amide) (PEBA)
Thermoplastic elastomers (TPE)
Gamma ray process
Electron beam process
Murray, Kieran
Effects of irradiation sterilisation on medical grade poly (ether-block-amide)
description The 2nd International Malaysia-Ireland Joint Symposium on Engineering, Science and Business 2012 (IMiEJS2012) jointly organized by Universiti Malaysia Perlis and Athlone Institute of Technology in collaboration with The Ministry of Higher Education (MOHE) Malaysia, Education Malaysia and Malaysia Postgraduates Student Association Ireland (MyPSI), 18th - 19th June 2012 at Putra World Trade Center (PWTC), Kuala Lumpur, Malaysia
format Other
author Murray, Kieran
author_facet Murray, Kieran
author_sort Murray, Kieran
title Effects of irradiation sterilisation on medical grade poly (ether-block-amide)
title_short Effects of irradiation sterilisation on medical grade poly (ether-block-amide)
title_full Effects of irradiation sterilisation on medical grade poly (ether-block-amide)
title_fullStr Effects of irradiation sterilisation on medical grade poly (ether-block-amide)
title_full_unstemmed Effects of irradiation sterilisation on medical grade poly (ether-block-amide)
title_sort effects of irradiation sterilisation on medical grade poly (ether-block-amide)
publisher Universiti Malaysia Perlis (UniMAP)
publishDate 2013
url http://dspace.unimap.edu.my/xmlui/handle/123456789/30832
_version_ 1643796389955633152
score 13.222552

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