Cover Image

Synthesis and characterisation of hydrogel based composites for bone regeneration

The 2nd International Malaysia-Ireland Joint Symposium on Engineering, Science and Business 2012 (IMiEJS2012) jointly organized by Universiti Malaysia Perlis and Athlone Institute of Technology in collaboration with The Ministry of Higher Education (MOHE) Malaysia, Education Malaysia and Malays...

Full description

Saved in:
Bibliographic Details
Main Authors: Killion, John, Gonzalez, Nelly, Geever, Luke, Devine, Declan, Kennedy, James, Higginbotham, Clement L.
Other Authors: jkillion@research.ait.ie
Format: Working Paper
Language:English
Published: Universiti Malaysia Perlis (UniMAP) 2013
Subjects:
Hydroxyapatite
Polyethylene glycol
Mechanical properties
Online Access:http://dspace.unimap.edu.my/xmlui/handle/123456789/27877
Tags: Add Tag
No Tags, Be the first to tag this record!
id my.unimap-27877
record_format dspace
spelling my.unimap-278772017-11-29T06:50:35Z Synthesis and characterisation of hydrogel based composites for bone regeneration Killion, John Gonzalez, Nelly Geever, Luke Devine, Declan Kennedy, James Higginbotham, Clement L. jkillion@research.ait.ie magargo7@etsid.upv.es Hydroxyapatite Polyethylene glycol Mechanical properties The 2nd International Malaysia-Ireland Joint Symposium on Engineering, Science and Business 2012 (IMiEJS2012) jointly organized by Universiti Malaysia Perlis and Athlone Institute of Technology in collaboration with The Ministry of Higher Education (MOHE) Malaysia, Education Malaysia and Malaysia Postgraduates Student Association Ireland (MyPSI), 18th - 19th June 2012 at Putra World Trade Center (PWTC), Kuala Lumpur, Malaysia. The current gold standard treatment for bone defects are biological grafts. Due to the inherent disadvantages for these biological grafts, a new synthetic alternative are being sought. Tissue engineering has shown great potential to replace the current treatments, due to its ability to provide structural support to the defect while promoting cellular attachment, proliferation and migration to help the formation new bone tissue. In this study, novel biocomposites of polyethylene glycol dimethacrylate (PEGDMA) and hydroxyapatite (HaP) were prepared via photopolymerisation. The objective of this study was to understand the effects of varying hydroxyapatite concentration had on the mechanical and thermal properties of the resultant biocomposite. The prepared hydrogel based composites were characterised by compression testing, gel fraction, differential scanning calorimetry (DSC) and swelling studies. Compression strength were tailored by very hydroxyapatite concentration (5 wt%-17.5 wt%). For example, variation in HaP concentration (A0-A17.5) resulted in an increase in Young’s modulus from 5.41 MPa to 5.89 MPa. 2013-09-03T02:10:49Z 2013-09-03T02:10:49Z 2012-06-18 Working Paper p. 1-8 978-967-5760-11-2 http://hdl.handle.net/123456789/27877 en Proceedings of the The 2nd International Malaysia-Ireland Joint Symposium on Engineering, Science and Business 2012 (IMiEJS2012); Universiti Malaysia Perlis (UniMAP)
institution Universiti Malaysia Perlis
building UniMAP Library
collection Institutional Repository
continent Asia
country Malaysia
content_provider Universiti Malaysia Perlis
content_source UniMAP Library Digital Repository
url_provider http://dspace.unimap.edu.my/
language English
topic Hydroxyapatite
Polyethylene glycol
Mechanical properties
spellingShingle Hydroxyapatite
Polyethylene glycol
Mechanical properties
Killion, John
Gonzalez, Nelly
Geever, Luke
Devine, Declan
Kennedy, James
Higginbotham, Clement L.
Synthesis and characterisation of hydrogel based composites for bone regeneration
description The 2nd International Malaysia-Ireland Joint Symposium on Engineering, Science and Business 2012 (IMiEJS2012) jointly organized by Universiti Malaysia Perlis and Athlone Institute of Technology in collaboration with The Ministry of Higher Education (MOHE) Malaysia, Education Malaysia and Malaysia Postgraduates Student Association Ireland (MyPSI), 18th - 19th June 2012 at Putra World Trade Center (PWTC), Kuala Lumpur, Malaysia.
author2 jkillion@research.ait.ie
author_facet jkillion@research.ait.ie
Killion, John
Gonzalez, Nelly
Geever, Luke
Devine, Declan
Kennedy, James
Higginbotham, Clement L.
format Working Paper
author Killion, John
Gonzalez, Nelly
Geever, Luke
Devine, Declan
Kennedy, James
Higginbotham, Clement L.
author_sort Killion, John
title Synthesis and characterisation of hydrogel based composites for bone regeneration
title_short Synthesis and characterisation of hydrogel based composites for bone regeneration
title_full Synthesis and characterisation of hydrogel based composites for bone regeneration
title_fullStr Synthesis and characterisation of hydrogel based composites for bone regeneration
title_full_unstemmed Synthesis and characterisation of hydrogel based composites for bone regeneration
title_sort synthesis and characterisation of hydrogel based composites for bone regeneration
publisher Universiti Malaysia Perlis (UniMAP)
publishDate 2013
url http://dspace.unimap.edu.my/xmlui/handle/123456789/27877
_version_ 1643802735713189888
score 13.214268

Similar Items