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Antimicrobial and Cytotoxic activities of Cerbera Odollam seeds and leaves

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Main Author: Mohamad Fadzreen, Mazlan
Other Authors: Prof. Madya Dr. Harbant Singh
Format: Learning Object
Language:English
Published: Universiti Malaysia Perlis (UniMAP) 2013
Subjects:
Antimicrobial
Cytotoxic
Cerbera Odollam
Fungus
Online Access:http://dspace.unimap.edu.my/xmlui/handle/123456789/27740
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spelling my.unimap-277402013-08-27T08:56:28Z Antimicrobial and Cytotoxic activities of Cerbera Odollam seeds and leaves Mohamad Fadzreen, Mazlan Prof. Madya Dr. Harbant Singh Antimicrobial Cytotoxic Cerbera Odollam Fungus Access is limited to UniMAP community. The ethanolic extractions from the parts (seeds and leaves) of Cerbera odollam were used in order to verify the antimicrobial activity and cytotoxicity by using different concentration of dilution prepared. The antimicrobial test was done to evaluate percentage of inhibition zone against Fusarium sp. colony growth on media with different concentration of extracts dilution. The concentrations prepared were in 500 ppm, 1625 ppm, 2750 ppm, 3875 ppm, and 5000 ppm after all the concentration being selected by using One Factor solution under Response Surface Methodology on Design of Expert software. The highest concentration of dilution of seeds and leaves at 5000 ppm were show highest percentage of inhibition zone, 86.67% (seeds) and 66.7% (leaves). For brine shrimp bioassay, the LC50 have been determining by appliying the ethanolic extraction with different concentration on brine shrimp (Artemia salina larvae). The concentrations used also have been determined by using One Factor solution under Response Surface Methodology on Design of Expert software until provided 10 ppm, 167.5 ppm, 325 ppm, 482.5 ppm and 640 ppm. The seeds and leaves of Cerbera odollam have killed 50 % of brine shrimp population tested at 190.54 mg/ml and 117.49 mg/ml, respectively which are indicated as LC50 values of Class IV of toxicity category, that are environmentally safe but the concentration should be used with caution. 2013-08-27T08:56:28Z 2013-08-27T08:56:28Z 2012-06 Learning Object http://hdl.handle.net/123456789/27740 en Universiti Malaysia Perlis (UniMAP) School of Bioprocess Engineering
institution Universiti Malaysia Perlis
building UniMAP Library
collection Institutional Repository
continent Asia
country Malaysia
content_provider Universiti Malaysia Perlis
content_source UniMAP Library Digital Repository
url_provider http://dspace.unimap.edu.my/
language English
topic Antimicrobial
Cytotoxic
Cerbera Odollam
Fungus
spellingShingle Antimicrobial
Cytotoxic
Cerbera Odollam
Fungus
Mohamad Fadzreen, Mazlan
Antimicrobial and Cytotoxic activities of Cerbera Odollam seeds and leaves
description Access is limited to UniMAP community.
author2 Prof. Madya Dr. Harbant Singh
author_facet Prof. Madya Dr. Harbant Singh
Mohamad Fadzreen, Mazlan
format Learning Object
author Mohamad Fadzreen, Mazlan
author_sort Mohamad Fadzreen, Mazlan
title Antimicrobial and Cytotoxic activities of Cerbera Odollam seeds and leaves
title_short Antimicrobial and Cytotoxic activities of Cerbera Odollam seeds and leaves
title_full Antimicrobial and Cytotoxic activities of Cerbera Odollam seeds and leaves
title_fullStr Antimicrobial and Cytotoxic activities of Cerbera Odollam seeds and leaves
title_full_unstemmed Antimicrobial and Cytotoxic activities of Cerbera Odollam seeds and leaves
title_sort antimicrobial and cytotoxic activities of cerbera odollam seeds and leaves
publisher Universiti Malaysia Perlis (UniMAP)
publishDate 2013
url http://dspace.unimap.edu.my/xmlui/handle/123456789/27740
_version_ 1643795392701136896
score 13.222552

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