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Production of Hydroxyapatite (HAp) Nanoparticles by wet chemistry methods for biomedical usage

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Bibliographic Details
Main Author: Taufiq Aminullah, Mokhtar
Other Authors: Dr. Midhat Nabil Ahmad Salimi
Format: Learning Object
Language:English
Published: Universiti Malaysia Perlis (UniMAP) 2013
Subjects:
Hydroxyapatite (HAp)
Hydroxyapatite (HAp) Nanoparticle
Human bone
Enamel
Bioactive material
Biomedical
Online Access:http://dspace.unimap.edu.my/xmlui/handle/123456789/27691
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spelling my.unimap-276912013-08-27T01:15:10Z Production of Hydroxyapatite (HAp) Nanoparticles by wet chemistry methods for biomedical usage Taufiq Aminullah, Mokhtar Dr. Midhat Nabil Ahmad Salimi Hydroxyapatite (HAp) Hydroxyapatite (HAp) Nanoparticle Human bone Enamel Bioactive material Biomedical Access is limited to UniMAP community. Hydroxyapatite, (HAp), Ca10(PO4)6(OH)2, is a physically occurring mineral found in the inorganic component of human bone and enamel. The basic elements of HAp are mainly calcium and phosphorous, with a stoichiometric calcium to phosphorous ratio of 1.67 capable of promoting intimate bone growth onto femoral implants. HAp is rendered a bioactive material since it has the ability to promote such growth with rapid fixation in what is also considered an osteoconductive process. The present study aims to produce HAp powders via the wet chemical precipitation technique, in order to evaluate the critical process parameters (mixing temperature, stirring rate, and Ca/P molar ratio) and their effect (main and interaction) on controlling the final HAp powder characteristics, such as, phase composition, crystallinity, crystallite size and particle size. 48.052 nm of HAp crystallite size was produced at 0.60 Ca/P molar ratio, 200 rpm of stirring rate and 600°C of mixing temperature. These powders were synthesised with a view to satisfying regulatory requirements which is favaourable particle size for biomedical usage is for the smallest particle as possible which is in this study the particle size should be in range of 30-50nm. These effects were quantified using Design of Experiments (Design Expert) to develop mathematical models, in terms of the chemical precipitation process parameters. The HAp nanoparticles were also analyzed by using Fourier Transform Infrared (FTIR), X-ray Diffractometer (XRD) and Scanning Electron Microscope (SEM). 2013-08-27T01:15:10Z 2013-08-27T01:15:10Z 2012-06 Learning Object http://hdl.handle.net/123456789/27691 en Universiti Malaysia Perlis (UniMAP) School of Bioprocess Engineering
institution Universiti Malaysia Perlis
building UniMAP Library
collection Institutional Repository
continent Asia
country Malaysia
content_provider Universiti Malaysia Perlis
content_source UniMAP Library Digital Repository
url_provider http://dspace.unimap.edu.my/
language English
topic Hydroxyapatite (HAp)
Hydroxyapatite (HAp) Nanoparticle
Human bone
Enamel
Bioactive material
Biomedical
spellingShingle Hydroxyapatite (HAp)
Hydroxyapatite (HAp) Nanoparticle
Human bone
Enamel
Bioactive material
Biomedical
Taufiq Aminullah, Mokhtar
Production of Hydroxyapatite (HAp) Nanoparticles by wet chemistry methods for biomedical usage
description Access is limited to UniMAP community.
author2 Dr. Midhat Nabil Ahmad Salimi
author_facet Dr. Midhat Nabil Ahmad Salimi
Taufiq Aminullah, Mokhtar
format Learning Object
author Taufiq Aminullah, Mokhtar
author_sort Taufiq Aminullah, Mokhtar
title Production of Hydroxyapatite (HAp) Nanoparticles by wet chemistry methods for biomedical usage
title_short Production of Hydroxyapatite (HAp) Nanoparticles by wet chemistry methods for biomedical usage
title_full Production of Hydroxyapatite (HAp) Nanoparticles by wet chemistry methods for biomedical usage
title_fullStr Production of Hydroxyapatite (HAp) Nanoparticles by wet chemistry methods for biomedical usage
title_full_unstemmed Production of Hydroxyapatite (HAp) Nanoparticles by wet chemistry methods for biomedical usage
title_sort production of hydroxyapatite (hap) nanoparticles by wet chemistry methods for biomedical usage
publisher Universiti Malaysia Perlis (UniMAP)
publishDate 2013
url http://dspace.unimap.edu.my/xmlui/handle/123456789/27691
_version_ 1643795455706923008
score 13.222552

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