Mixing in the mechanically agitated bioreactor: ‘A matter of being stirred, not shaken’

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Main Author: Shaliza, Ibrahim, Prof.
Other Authors: shaliza@um.edu.my
Format: Article
Language:English
Published: The Institution of Engineers, Malaysia 2011
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Online Access:http://dspace.unimap.edu.my/xmlui/handle/123456789/13646
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spelling my.unimap-136462011-09-04T04:25:07Z Mixing in the mechanically agitated bioreactor: ‘A matter of being stirred, not shaken’ Shaliza, Ibrahim, Prof. shaliza@um.edu.my Impeller Mixing power Multiphase mixing Rheological effects Stirred vessel Link to publisher's homepage at http://www.myiem.org.my/ Variations in the system parameters can in fact give rise to significant differences in mixing requirement, and failure to operate at the right conditions can result in undesirable outcomes. Biological systems are sensitive to bioreactor hydrodynamics since it directly affects transport processes at the molecular level. In addition, extracellular products and filamentous microbes contribute to drastic changes in the broth characteristics over the course of fermentation, that would in turn alter the mixing needs. Poor mixing or over mixing can both have adverse effects on product quality, but inefficient equipment design leading to excessive energy requirement often goes unnoticed if there are no apparent effects on the product. This paper summarizes the basic considerations to be made for given mixing duties so as to enable operations in a calculated rather than random manner. 2011-09-04T04:25:07Z 2011-09-04T04:25:07Z 2007-09 Article The Journal of the Institution of Engineers, Malaysia, vol. 68(3), 2007, pages 43-47 0126-513X http://myiem.org.my/content/iem_journal_2007-178.aspx http://hdl.handle.net/123456789/13646 en The Institution of Engineers, Malaysia
institution Universiti Malaysia Perlis
building UniMAP Library
collection Institutional Repository
continent Asia
country Malaysia
content_provider Universiti Malaysia Perlis
content_source UniMAP Library Digital Repository
url_provider http://dspace.unimap.edu.my/
language English
topic Impeller
Mixing power
Multiphase mixing
Rheological effects
Stirred vessel
spellingShingle Impeller
Mixing power
Multiphase mixing
Rheological effects
Stirred vessel
Shaliza, Ibrahim, Prof.
Mixing in the mechanically agitated bioreactor: ‘A matter of being stirred, not shaken’
description Link to publisher's homepage at http://www.myiem.org.my/
author2 shaliza@um.edu.my
author_facet shaliza@um.edu.my
Shaliza, Ibrahim, Prof.
format Article
author Shaliza, Ibrahim, Prof.
author_sort Shaliza, Ibrahim, Prof.
title Mixing in the mechanically agitated bioreactor: ‘A matter of being stirred, not shaken’
title_short Mixing in the mechanically agitated bioreactor: ‘A matter of being stirred, not shaken’
title_full Mixing in the mechanically agitated bioreactor: ‘A matter of being stirred, not shaken’
title_fullStr Mixing in the mechanically agitated bioreactor: ‘A matter of being stirred, not shaken’
title_full_unstemmed Mixing in the mechanically agitated bioreactor: ‘A matter of being stirred, not shaken’
title_sort mixing in the mechanically agitated bioreactor: ‘a matter of being stirred, not shaken’
publisher The Institution of Engineers, Malaysia
publishDate 2011
url http://dspace.unimap.edu.my/xmlui/handle/123456789/13646
_version_ 1643790946851094528
score 13.214268