Cytotoxicity and mechanisms of cell death of selected marine sponges on human breast cancer cell line, MCF-7

Breast cancer is the most frequently diagnosed cancers among women worldwide. However, to date, research is still ongoing to find alternative drugs to the current chemotherapeutic drugs available in the market. Marine environment offers vast diversity of living organisms that provide compounds with...

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Main Author: Hidayah, Tuti
Format: Thesis
Language:English
Published: Terengganu: Universiti Malaysia Terengganu 2014
Subjects:
Online Access:http://dspace.psnz.umt.edu.my/xmlui/handle/123456789/3054
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spelling my.umt.ir-30542014-05-19T07:06:32Z Cytotoxicity and mechanisms of cell death of selected marine sponges on human breast cancer cell line, MCF-7 Hidayah, Tuti RC 268.44 .B73 H5 2013 Hidayah, Tuti Tesis FST 2013 BRCA genes Breast cancer is the most frequently diagnosed cancers among women worldwide. However, to date, research is still ongoing to find alternative drugs to the current chemotherapeutic drugs available in the market. Marine environment offers vast diversity of living organisms that provide compounds with impressive structural diversity, highly specific biological activities and drug-like properties. Therefore, the main aim of this study was to determine the cytotoxic effects and mechanisms of cell death exerted by marine sponges on human breast cancer cell line, MCF-7. In this study, six marine sponges from four species, namely Aaptos sp., Stryphuous ponderosus., Theonella sp., and Xestospongia sp., were used. 2014-05-19T07:06:32Z 2014-05-19T07:06:32Z 2013-05 Thesis http://dspace.psnz.umt.edu.my/xmlui/handle/123456789/3054 en application/pdf application/pdf Terengganu: Universiti Malaysia Terengganu
institution Universiti Malaysia Terengganu
building Perpustakaan Sultanah Nur Zahirah
collection Institutional Repository
continent Asia
country Malaysia
content_provider Universiti Malaysia Terengganu
content_source UMT-IR
url_provider http://umt-ir.umt.edu.my:8080/
language English
topic RC 268.44 .B73 H5 2013
Hidayah, Tuti
Tesis FST 2013
BRCA genes
spellingShingle RC 268.44 .B73 H5 2013
Hidayah, Tuti
Tesis FST 2013
BRCA genes
Hidayah, Tuti
Cytotoxicity and mechanisms of cell death of selected marine sponges on human breast cancer cell line, MCF-7
description Breast cancer is the most frequently diagnosed cancers among women worldwide. However, to date, research is still ongoing to find alternative drugs to the current chemotherapeutic drugs available in the market. Marine environment offers vast diversity of living organisms that provide compounds with impressive structural diversity, highly specific biological activities and drug-like properties. Therefore, the main aim of this study was to determine the cytotoxic effects and mechanisms of cell death exerted by marine sponges on human breast cancer cell line, MCF-7. In this study, six marine sponges from four species, namely Aaptos sp., Stryphuous ponderosus., Theonella sp., and Xestospongia sp., were used.
format Thesis
author Hidayah, Tuti
author_facet Hidayah, Tuti
author_sort Hidayah, Tuti
title Cytotoxicity and mechanisms of cell death of selected marine sponges on human breast cancer cell line, MCF-7
title_short Cytotoxicity and mechanisms of cell death of selected marine sponges on human breast cancer cell line, MCF-7
title_full Cytotoxicity and mechanisms of cell death of selected marine sponges on human breast cancer cell line, MCF-7
title_fullStr Cytotoxicity and mechanisms of cell death of selected marine sponges on human breast cancer cell line, MCF-7
title_full_unstemmed Cytotoxicity and mechanisms of cell death of selected marine sponges on human breast cancer cell line, MCF-7
title_sort cytotoxicity and mechanisms of cell death of selected marine sponges on human breast cancer cell line, mcf-7
publisher Terengganu: Universiti Malaysia Terengganu
publishDate 2014
url http://dspace.psnz.umt.edu.my/xmlui/handle/123456789/3054
_version_ 1738395447155752960
score 13.214268