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Isolation and identification of bioactive compounds from seaweed Sargassum ilicifolium

Three species or Sargassum sp. (S. ilicifolium, S. pofycystum and S. oligocystum) have been screened for antioxidant (DPPH method), cytotoxicity (MTT Assay), antimicrobial (Disc Diffus ion Method) and anti-amoebic bioactivities. All methanol crude extracts showed DPPH free radical scavenging, cytoto...

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Bibliographic Details
Main Author: Afnani Alwi @Ali
Format: Thesis
Language:English
Published: Terengganu: Universiti Malaysia Terengganu 2013
Subjects:
QK 569 .S2 A5 2012
Afnani Alwi @Ali
Tesis FST 2012
Sargassum > Malaysia
Sargassaceae > Malaysia
Online Access:http://dspace.psnz.umt.edu.my/xmlui/handle/123456789/2439
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record_format eprints
spelling my.umt.ir-24392016-03-16T06:48:56Z Isolation and identification of bioactive compounds from seaweed Sargassum ilicifolium Afnani Alwi @Ali QK 569 .S2 A5 2012 Afnani Alwi @Ali Tesis FST 2012 Sargassum -- Malaysia Sargassaceae -- Malaysia Three species or Sargassum sp. (S. ilicifolium, S. pofycystum and S. oligocystum) have been screened for antioxidant (DPPH method), cytotoxicity (MTT Assay), antimicrobial (Disc Diffus ion Method) and anti-amoebic bioactivities. All methanol crude extracts showed DPPH free radical scavenging, cytotoxic to several cell lines which include HL-60 (leukemic) and MCF-7 (breast cancer), anti-bacterial and anti-amoebic activity. However methanol ex tract of S. oligocystwn is inactive against all microbes tested. Only S.ilicifolium elected to be investigate further, based on their promising bioactivity results and the availability of the sample. 2013-06-12T02:09:17Z 2013-06-12T02:09:17Z 2012-09 Thesis http://dspace.psnz.umt.edu.my/xmlui/handle/123456789/2439 en application/pdf application/pdf Terengganu: Universiti Malaysia Terengganu
institution Universiti Malaysia Terengganu
building Perpustakaan Sultanah Nur Zahirah
collection Institutional Repository
continent Asia
country Malaysia
content_provider Universiti Malaysia Terengganu
content_source UMT-IR
url_provider http://umt-ir.umt.edu.my:8080/
language English
topic QK 569 .S2 A5 2012
Afnani Alwi @Ali
Tesis FST 2012
Sargassum -- Malaysia
Sargassaceae -- Malaysia
spellingShingle QK 569 .S2 A5 2012
Afnani Alwi @Ali
Tesis FST 2012
Sargassum -- Malaysia
Sargassaceae -- Malaysia
Afnani Alwi @Ali
Isolation and identification of bioactive compounds from seaweed Sargassum ilicifolium
description Three species or Sargassum sp. (S. ilicifolium, S. pofycystum and S. oligocystum) have been screened for antioxidant (DPPH method), cytotoxicity (MTT Assay), antimicrobial (Disc Diffus ion Method) and anti-amoebic bioactivities. All methanol crude extracts showed DPPH free radical scavenging, cytotoxic to several cell lines which include HL-60 (leukemic) and MCF-7 (breast cancer), anti-bacterial and anti-amoebic activity. However methanol ex tract of S. oligocystwn is inactive against all microbes tested. Only S.ilicifolium elected to be investigate further, based on their promising bioactivity results and the availability of the sample.
format Thesis
author Afnani Alwi @Ali
author_facet Afnani Alwi @Ali
author_sort Afnani Alwi @Ali
title Isolation and identification of bioactive compounds from seaweed Sargassum ilicifolium
title_short Isolation and identification of bioactive compounds from seaweed Sargassum ilicifolium
title_full Isolation and identification of bioactive compounds from seaweed Sargassum ilicifolium
title_fullStr Isolation and identification of bioactive compounds from seaweed Sargassum ilicifolium
title_full_unstemmed Isolation and identification of bioactive compounds from seaweed Sargassum ilicifolium
title_sort isolation and identification of bioactive compounds from seaweed sargassum ilicifolium
publisher Terengganu: Universiti Malaysia Terengganu
publishDate 2013
url http://dspace.psnz.umt.edu.my/xmlui/handle/123456789/2439
_version_ 1738395510315679744
score 13.222552

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