IMiD/CELMoD-induced growth suppression of adult T-cell leukemia/lymphoma cells via cereblon through downregulation of target proteins and their downstream effectors
Adult T-cell leukemia/lymphoma (ATL) is an aggressive T-cell neoplasia associated with human T-cell leukemia virus type 1 (HTLV-1) infection and has an extremely poor prognosis. Lenalidomide (LEN; a second-generation immunomodulatory drug [IMiD]) has been employed as an additional therapeutic option...
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Main Authors: | Yu Wang, Shunsuke Shimosaki, Emi Ikebe, Hidekatsu Iha, Jun-ichi Yamamoto, Nichole Fife, Tomonaga Ichikawa, Mitsuo Hori, Masao Ogata, Yoshiyuki Tsukamoto, Naoki Hijiya, Masatsugu Moriyama, Shotaro Hagiwara, Shuichi Kusano, Masumichi Saito, Kamruddin Ahmed, Akira Nishizono, Hiroshi Handa, Kazuhiro Morishita |
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Format: | Article |
Language: | English English |
Published: |
Frontiers Media SA
2024
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Subjects: | |
Online Access: | https://eprints.ums.edu.my/id/eprint/38798/1/ABSTRACT.pdf https://eprints.ums.edu.my/id/eprint/38798/2/FULL%20TEXT.pdf https://eprints.ums.edu.my/id/eprint/38798/ https://doi.org/10.3389/fonc.2023.1272528 |
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