The Potential Chemo Preventive Effect of Andrographis paniculata on 1,2- Dimethylhydrazine and High-Fat-Diet-Induced Colorectal Cancer in Sprague Dawley Rats

• Main Authors: Tharani Subarmaniam, Rusydatul Nabila Mahmad Rusli, Kokila Vani Perumal, Yoke Keong Yong, Siti Hadizah, Fezah Othman, Khaled Salem, Nurul Husna Shafie, Rosnani Hasham, Khoo Boon Yin, Khairul Kamilah Abdul Kadir, Hasnah Bahari, Zainul Amiruddin Zakaria
• Format: Article
• Language: English; English
• Published: MDPI AG, Basel, Switzerland 2023
• Subjects: Q1-295 General; RS153-441 Materia medica
• Online Access: https://eprints.ums.edu.my/id/eprint/38574/1/ABSTRACT.pdf; https://eprints.ums.edu.my/id/eprint/38574/2/FULL%20TEXT.pdf; https://eprints.ums.edu.my/id/eprint/38574/; https://doi.org/10.3390/ijms24065224

Colorectal cancer (CRC) is responsible for a notable rise in the overall mortality rate. Obesity is found to be one of the main factors behind CRC development. Andrographis paniculata is a herbaceous plant famous for its medicinal properties, particularly in Southeast Asia for its anti-cancer proper...