Design, synthesis, in vitro antiproliferative effect and in situ molecular docking studies of a series of new benzoquinoline derivatives

• Main Authors: Abdulrashid Umar, Hassan M. Faidallah, Qamar Uddin Ahmed, Khalid.A. Alamry, Sayeed Mukhtar, Meshari A. Alsharif, Syed Najmul Hejaz Azmi, Humaira Parveen, Zainul Amiruddin Zakaria, Mostafa A. Hussien
• Format: Article
• Language: English; English
• Published: Elsevier 2022
• Subjects: QD1-999 Chemistry
• Online Access: https://eprints.ums.edu.my/id/eprint/38373/1/ABSTRACT.pdf; https://eprints.ums.edu.my/id/eprint/38373/2/FULLTEXT.pdf; https://eprints.ums.edu.my/id/eprint/38373/; https://doi.org/10.1016/j.jksus.2022.102003

Quinoline derivatives have been reported to possess multi-therapeutic potential owing to the manifestations of different pharmacological effects. The current research work describes about the design and synthesis of a series of novel benzoquinoline analogues with an objective to evaluate their antip...