COVID-19 Treatment—Current Status, Advances, and Gap
COVID-19, which emerged in December 2019, was declared a global pandemic by the World Health Organization (WHO) in March 2020. The disease was caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). It has caused millions of deaths worldwide and caused social and economic disruption....
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Online Access: | https://eprints.ums.edu.my/id/eprint/35232/1/Abstract.pdf https://eprints.ums.edu.my/id/eprint/35232/2/Full%20text.pdf https://eprints.ums.edu.my/id/eprint/35232/ https://www.mdpi.com/2076-0817/11/10/1201 https://doi.org/10.3390/pathogens11101201 |
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my.ums.eprints.352322023-03-23T02:12:51Z https://eprints.ums.edu.my/id/eprint/35232/ COVID-19 Treatment—Current Status, Advances, and Gap Chian Ho Lee, Ping Chin RA643-645 Disease (Communicable and noninfectious) and public health RA648.5-767 Epidemics. Epidemiology. Quarantine. Disinfection COVID-19, which emerged in December 2019, was declared a global pandemic by the World Health Organization (WHO) in March 2020. The disease was caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). It has caused millions of deaths worldwide and caused social and economic disruption. While clinical trials on therapeutic drugs are going on in an Accelerating COVID-19 Therapeutic Interventions and Vaccines (ACTIV) public–private partnership collaboration, current therapeutic approaches and options to counter COVID-19 remain few. Therapeutic drugs include the FDA-approved antiviral drugs, Remdesivir, and an immune modulator, Baricitinib. Hence, therapeutic approaches and alternatives for COVID-19 treatment need to be broadened. This paper discusses efforts in approaches to find treatment for COVID-19, such as inhibiting viral entry and disrupting the virus life cycle, and highlights the gap that needs to be filled in these approaches. MDPI 2022 Article PeerReviewed text en https://eprints.ums.edu.my/id/eprint/35232/1/Abstract.pdf text en https://eprints.ums.edu.my/id/eprint/35232/2/Full%20text.pdf Chian Ho and Lee, Ping Chin (2022) COVID-19 Treatment—Current Status, Advances, and Gap. Pathogens, 11. pp. 1-15. ISSN 2076-0817 https://www.mdpi.com/2076-0817/11/10/1201 https://doi.org/10.3390/pathogens11101201 |
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RA643-645 Disease (Communicable and noninfectious) and public health RA648.5-767 Epidemics. Epidemiology. Quarantine. Disinfection Chian Ho Lee, Ping Chin COVID-19 Treatment—Current Status, Advances, and Gap |
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COVID-19, which emerged in December 2019, was declared a global pandemic by the World Health Organization (WHO) in March 2020. The disease was caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). It has caused millions of deaths worldwide and caused social and economic disruption. While clinical trials on therapeutic drugs are going on in an Accelerating COVID-19 Therapeutic Interventions and Vaccines (ACTIV) public–private partnership collaboration, current therapeutic approaches and options to counter COVID-19 remain few. Therapeutic drugs include the FDA-approved antiviral drugs, Remdesivir, and an immune modulator, Baricitinib. Hence, therapeutic approaches and alternatives for COVID-19 treatment need to be broadened. This paper discusses efforts in approaches to find treatment for COVID-19, such as inhibiting viral entry and disrupting the virus life cycle, and highlights the gap that needs to be filled in these approaches. |
format |
Article |
author |
Chian Ho Lee, Ping Chin |
author_facet |
Chian Ho Lee, Ping Chin |
author_sort |
Chian Ho |
title |
COVID-19 Treatment—Current Status, Advances, and Gap |
title_short |
COVID-19 Treatment—Current Status, Advances, and Gap |
title_full |
COVID-19 Treatment—Current Status, Advances, and Gap |
title_fullStr |
COVID-19 Treatment—Current Status, Advances, and Gap |
title_full_unstemmed |
COVID-19 Treatment—Current Status, Advances, and Gap |
title_sort |
covid-19 treatment—current status, advances, and gap |
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MDPI |
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2022 |
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https://eprints.ums.edu.my/id/eprint/35232/1/Abstract.pdf https://eprints.ums.edu.my/id/eprint/35232/2/Full%20text.pdf https://eprints.ums.edu.my/id/eprint/35232/ https://www.mdpi.com/2076-0817/11/10/1201 https://doi.org/10.3390/pathogens11101201 |
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13.160551 |