Modulation of POPDC1 expression by Phenothiazine and Trifluoperazine suppress colon cancer growth and migration

• Main Authors: Fiona Macniesia Thomas, Suhaini Sudi, Falah Abass Mohamed Salih, Praneetha Palasuberniam, Latifah Suali, Mohd. Hijaz Mohd. Sani, Caroline Sunggip
• 格式: Article
• 語言: English; English
• 出版: Asian Pacific Organization for Cancer Prevention (APOCP) 2022
• 主題: RC254-282 Neoplasms. Tumors. Oncology Including cancer and carcinogens
• 在線閱讀: https://eprints.ums.edu.my/id/eprint/34579/2/FULL%20TEXT.pdf; https://eprints.ums.edu.my/id/eprint/34579/1/ABSTRACT.pdf; https://eprints.ums.edu.my/id/eprint/34579/; http://journal.waocp.org/article_90242_a938dabf54d9ec31d75362e66fa529ec.pdf; https://doi.org/10.31557/APJCP.2022.23.8.2863

Objective: The aim of this study was to investigate the effects of CaM antagonist, PTZ, and TFP on cell proliferation and migration of colon cancer cells and its impact on POPDC protein expression. Methods: The 50% inhibitory concentration (IC50 ) of PTZ and TFP in SW1116, SW480, HCT-15, and COLO205...