High-throughput metabolomics reveals dysregulation of hydrophobic metabolomes in cancer cell lines by Eleusine indica

• Main Authors: Puah, Perng Yang, Lee, Dexter Jiunn Herng, Puah, Soo Huan, Nik Amin Sahid Nik Lah, Ling, Yee Soon, Fong, Siat Yee
• Format: Article
• Language: English; English
• Published: Nature Publishing Group 2022
• Subjects: RC254-282 Neoplasms. Tumors. Oncology Including cancer and carcinogens
• Online Access: https://eprints.ums.edu.my/id/eprint/34200/1/High-throughput%20metabolomics%20reveals%20dysregulation%20of%20hydrophobic%20metabolomes%20in%20cancer%20cell%20lines%20by%20Eleusine%20indica.ABSTRACT.pdf; https://eprints.ums.edu.my/id/eprint/34200/2/High-throughput%20metabolomics%20reveals%20dysregulation%20of%20hydrophobic%20metabolomes%20in%20cancer%20cell%20lines%20by%20Eleusine%20indica.pdf; https://eprints.ums.edu.my/id/eprint/34200/; https://www.nature.com/articles/s41598-022-13575-6; https://doi.org/10.1038/s41598-022-13575-6

Eleusine indica, which is used in traditional medicine, exhibits antiproliferative activity against several cancer cell lines. However, metabolomic studies to evaluate the metabolite changes induced by E. indica in cancer cells are still lacking. The present study investigated the anticancer effects...