Design and Synthesis of Different Aryl Substituted 1,3,4-Oxadiazole-imidazo[1,5-a]pyridine Derivatives as Anticancer Agents

A new series of 1,3,4-oxadiazole incorporated imidazo[1,5-a]pyridine derivatives was prepared. Anticancer activity of all the obtained compounds was investigated by employing MTT assay. Among them, six compounds showed most prominent anticancer activity than etoposide.

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Main Authors: Dandamudi Srilaxmi, Alugubelli Gopi Reddy, Reddymasu Sireesha, Pasupuleti Visweswara Rao, M. Ravi Kiran, Deepti Kolli, Mandava Venkata Basaveswara Rao
Format: Article
Language:English
English
Published: Pleiades Publishing 2022
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Online Access:https://eprints.ums.edu.my/id/eprint/34182/1/FULL%20TEXT.pdf
https://eprints.ums.edu.my/id/eprint/34182/2/ABSTRACT.pdf
https://eprints.ums.edu.my/id/eprint/34182/
https://www.pleiades.online/abstract/genchem/22/genchem0891_abstract.pdf
https://doi.org/10.1134/S107036322205019X
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spelling my.ums.eprints.341822022-09-29T03:14:23Z https://eprints.ums.edu.my/id/eprint/34182/ Design and Synthesis of Different Aryl Substituted 1,3,4-Oxadiazole-imidazo[1,5-a]pyridine Derivatives as Anticancer Agents Dandamudi Srilaxmi Alugubelli Gopi Reddy Reddymasu Sireesha Pasupuleti Visweswara Rao M. Ravi Kiran Deepti Kolli Mandava Venkata Basaveswara Rao RC254-282 Neoplasms. Tumors. Oncology Including cancer and carcinogens RS400-431 Pharmaceutical chemistry A new series of 1,3,4-oxadiazole incorporated imidazo[1,5-a]pyridine derivatives was prepared. Anticancer activity of all the obtained compounds was investigated by employing MTT assay. Among them, six compounds showed most prominent anticancer activity than etoposide. Pleiades Publishing 2022 Article PeerReviewed text en https://eprints.ums.edu.my/id/eprint/34182/1/FULL%20TEXT.pdf text en https://eprints.ums.edu.my/id/eprint/34182/2/ABSTRACT.pdf Dandamudi Srilaxmi and Alugubelli Gopi Reddy and Reddymasu Sireesha and Pasupuleti Visweswara Rao and M. Ravi Kiran and Deepti Kolli and Mandava Venkata Basaveswara Rao (2022) Design and Synthesis of Different Aryl Substituted 1,3,4-Oxadiazole-imidazo[1,5-a]pyridine Derivatives as Anticancer Agents. Russian Journal of General Chemistry, 92. pp. 891-897. ISSN 1070-3632 (P-ISSN) , 1608-3350 (E-ISSN) https://www.pleiades.online/abstract/genchem/22/genchem0891_abstract.pdf https://doi.org/10.1134/S107036322205019X
institution Universiti Malaysia Sabah
building UMS Library
collection Institutional Repository
continent Asia
country Malaysia
content_provider Universiti Malaysia Sabah
content_source UMS Institutional Repository
url_provider http://eprints.ums.edu.my/
language English
English
topic RC254-282 Neoplasms. Tumors. Oncology Including cancer and carcinogens
RS400-431 Pharmaceutical chemistry
spellingShingle RC254-282 Neoplasms. Tumors. Oncology Including cancer and carcinogens
RS400-431 Pharmaceutical chemistry
Dandamudi Srilaxmi
Alugubelli Gopi Reddy
Reddymasu Sireesha
Pasupuleti Visweswara Rao
M. Ravi Kiran
Deepti Kolli
Mandava Venkata Basaveswara Rao
Design and Synthesis of Different Aryl Substituted 1,3,4-Oxadiazole-imidazo[1,5-a]pyridine Derivatives as Anticancer Agents
description A new series of 1,3,4-oxadiazole incorporated imidazo[1,5-a]pyridine derivatives was prepared. Anticancer activity of all the obtained compounds was investigated by employing MTT assay. Among them, six compounds showed most prominent anticancer activity than etoposide.
format Article
author Dandamudi Srilaxmi
Alugubelli Gopi Reddy
Reddymasu Sireesha
Pasupuleti Visweswara Rao
M. Ravi Kiran
Deepti Kolli
Mandava Venkata Basaveswara Rao
author_facet Dandamudi Srilaxmi
Alugubelli Gopi Reddy
Reddymasu Sireesha
Pasupuleti Visweswara Rao
M. Ravi Kiran
Deepti Kolli
Mandava Venkata Basaveswara Rao
author_sort Dandamudi Srilaxmi
title Design and Synthesis of Different Aryl Substituted 1,3,4-Oxadiazole-imidazo[1,5-a]pyridine Derivatives as Anticancer Agents
title_short Design and Synthesis of Different Aryl Substituted 1,3,4-Oxadiazole-imidazo[1,5-a]pyridine Derivatives as Anticancer Agents
title_full Design and Synthesis of Different Aryl Substituted 1,3,4-Oxadiazole-imidazo[1,5-a]pyridine Derivatives as Anticancer Agents
title_fullStr Design and Synthesis of Different Aryl Substituted 1,3,4-Oxadiazole-imidazo[1,5-a]pyridine Derivatives as Anticancer Agents
title_full_unstemmed Design and Synthesis of Different Aryl Substituted 1,3,4-Oxadiazole-imidazo[1,5-a]pyridine Derivatives as Anticancer Agents
title_sort design and synthesis of different aryl substituted 1,3,4-oxadiazole-imidazo[1,5-a]pyridine derivatives as anticancer agents
publisher Pleiades Publishing
publishDate 2022
url https://eprints.ums.edu.my/id/eprint/34182/1/FULL%20TEXT.pdf
https://eprints.ums.edu.my/id/eprint/34182/2/ABSTRACT.pdf
https://eprints.ums.edu.my/id/eprint/34182/
https://www.pleiades.online/abstract/genchem/22/genchem0891_abstract.pdf
https://doi.org/10.1134/S107036322205019X
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score 13.160551