Association between Leptin (G2548A) and Leptin Receptor (Q223R) Polymorphisms with Plasma Leptin, BMI, Stress, Sleep and Eating Patterns among the Multiethnic Young Malaysian Adult Population from a Healthcare University

• Main Authors: Jaiprakash Mohanraj, D’Souza, Urban J. A., Fong, Alison Siat Yee, Karkada, Ivan Rolland, Heethal Jaiprakash
• Format: Article
• Language: English; English
• Published: Multidisciplinary Digital Publishing Institute (MDPI) 2022
• Subjects: RC581-951 Specialties of internal medicine
• Online Access: https://eprints.ums.edu.my/id/eprint/34094/1/Association%20between%20Leptin%20_G2548A_%20and%20Leptin%20Receptor%20_Q223R_%20Polymorphisms.pdf; https://eprints.ums.edu.my/id/eprint/34094/2/Association%20between%20Leptin%20_G2548A_%20and%20Leptin%20Receptor%20_Q223R_%20Polymorphisms%20_ABSTRACT.pdf; https://eprints.ums.edu.my/id/eprint/34094/; https://www.mdpi.com/1660-4601/19/14/8862/htm; https://doi.org/10.3390/ijerph19148862

Relative leptin resistance in childhood to absolute leptin resistance in maturity suggests sleep, eating behaviour, and the psychological state as probable causes. The current body of research provides inconclusive evidence linking G2548A and Q223R to obesity. Furthermore, we could find very little...