Ethyl acetate partition obtained from the methanol extract of Muntingia calabura leaf exerts effective in vitro antiproliferative activity against the HT-29 colon cancer

• Main Authors: Zainul Amirudin Zakaria, Nur Liana Md Nasir, Noorsyaza Eddrina Kamsani, Huzwah Khaza’ai, Lilis Sulistyorini, Roro Azizah
• Format: Article
• Language: English; English
• Published: Blacpma 2022
• Subjects: RC254-282 Neoplasms. Tumors. Oncology Including cancer and carcinogens; RV1-431 Botanic, Thomsonian, and eclectic medicine
• Online Access: https://eprints.ums.edu.my/id/eprint/33276/1/Ethyl%20acetate%20partition%20obtained%20from%20the%20methanol%20extract%20of%20Muntingia%20calabura%20leaf%20exerts%20effective%20in%20vitro%20antiproliferative%20activity%20against%20the%20HT-29%20colon%20cancer%20.pdf; https://eprints.ums.edu.my/id/eprint/33276/2/Ethyl%20acetate%20partition%20obtained%20from%20the%20methanol%20extract%20of%20Muntingia%20calabura%20leaf%20exerts%20effective%20in%20vitro%20antiproliferative%20activity%20against%20the%20HT-29%20colon%20cancer%201.pdf; https://eprints.ums.edu.my/id/eprint/33276/; https://www.blacpma.ms-editions.cl/index.php/blacpma/article/view/310/318; https://doi.org/10.37360/blacpma.22.21.5.41

Methanol extract of Muntingia calabura L. leaf (MEMCL) has been shown to exert the antiproliferative activity against the HT-29 (human colon adenocarcinoma) cell line. To further investigate on the medicinal potential of this plant, MEMCL was sequentially partitioned to obtain the petroleum ether, e...