Thermodynamic stability, in-vitro permeability, and in-silico molecular modeling of the optimal Elaeis guineensis leaves extract water-in-oil nanoemulsion

• Main Authors: Nissha Bharrathi Romes, Roswanira Abdul Wahab, Mariani Abdul Hamid, Habeebat Adekilekun Oyewusi, Nurul Huda, Rovina Kobun
• Format: Article
• Language: English; English
• Published: Nature Publishing 2021
• Subjects: SB1-1110 Plant culture; TP1-1185 Chemical technology
• Online Access: https://eprints.ums.edu.my/id/eprint/32412/1/Thermodynamic%20stability%2C%20in-vitro%20permeability%2C%20and%20in-silico%20molecular%20modeling%20of%20the%20optimal%20Elaeis%20guineensis%20leaves%20extract%20water-in-oil%20nanoemulsion.pdf; https://eprints.ums.edu.my/id/eprint/32412/3/Thermodynamic%20stability%2C%20in-vitro%20permeability%2C%20and%20in-silico%20molecular%20modeling%20of%20the%20optimal%20Elaeis%20guineensis%20leaves%20extract%20water-in-oil%20nanoemulsion%20_ABSTRACT.pdf; https://eprints.ums.edu.my/id/eprint/32412/; https://www.nature.com/articles/s41598-021-00409-0; https://doi.org/10.1038/s41598-021-00409-0

Nanoemulsion is a delivery system used to enhance bioavailability of plant-based compounds across the stratum corneum. Elaeis guineensis leaves are rich source of polyphenolic antioxidants, viz. gallic acid and catechin. The optimal E. guineensis leaves extract water-in-oil nanoemulsion was stable a...