Integration of RNA-Seq and proteomics data identifies glioblastoma multiforme surfaceome signature

• Main Authors: Saiful Effendi Syafruddin, Wan Fahmi Wan Mohamad Nazarie, Nurshahirah Ashikin Moidu, Bee, Hong Soon, M. Aiman Mohtar
• Format: Article
• Language: English; English
• Published: Springer Nature 2021
• Subjects: Q1-390 Science (General); QP1-(981) Physiology
• Online Access: https://eprints.ums.edu.my/id/eprint/32193/1/Integration%20of%20RNA-Seq%20and%20proteomics%20data%20identifies%20glioblastoma%20multiforme%20surfaceome%20signature.pdf; https://eprints.ums.edu.my/id/eprint/32193/2/Integration%20of%20RNA-Seq%20and%20proteomics%20data%20identifies%20glioblastoma%20multiforme%20surfaceome%20signature1.pdf; https://eprints.ums.edu.my/id/eprint/32193/; https://bmccancer.biomedcentral.com/articles/10.1186/s12885-021-08591-0; https://doi.org/10.1186/s12885-021-08591-0

Background: Glioblastoma multiforme (GBM) is a highly lethal, stage IV brain tumour with a prevalence of approximately 2 per 10,000 people globally. The cell surface proteins or surfaceome serve as information gateway in many oncogenic signalling pathways and are important in modulating cancer pheno...