Multifaceted phytogenic silver nanoparticles by an insectivorous plant drosera spatulata Labill var. bakoensis and its potential therapeutic applications
The current investigation highlights the green synthesis of silver nanoparticles (AgNPs) by the insectivorous plant Drosera spatulata Labill var. bakoensis, which is the first of its kind. The biosynthesized nanoparticles revealed a UV visible surface plasmon resonance (SPR) band at 427 nm. The natu...
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2021
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Online Access: | https://eprints.ums.edu.my/id/eprint/31879/1/Multifaceted%20phytogenic%20silver%20nanoparticles%20by%20an%20insectivorous%20plant%20drosera%20spatulata%20Labill%20var.%20bakoensis%20and%20its%20potential%20therapeutic%20applications.pdf https://eprints.ums.edu.my/id/eprint/31879/2/Multifaceted%20phytogenic%20silver%20nanoparticles%20by%20an%20insectivorous%20plant%20drosera%20spatulata%20Labill%20var.%20bakoensis%20and%20its%20potential%20therapeutic%20applications_ABSTRACT.pdf https://eprints.ums.edu.my/id/eprint/31879/ https://www.nature.com/articles/s41598-021-01281-8.pdf?proof=t%25C2%25A0 https://doi.org/10.1038/s41598-021-01281-8 |
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my.ums.eprints.318792022-03-17T06:29:06Z https://eprints.ums.edu.my/id/eprint/31879/ Multifaceted phytogenic silver nanoparticles by an insectivorous plant drosera spatulata Labill var. bakoensis and its potential therapeutic applications Susmila Aparna Gaddam Venkata Subbaiah Kotakadi Gunasekhar Kalavakunta Subramanyam Josthna Penchalaneni Varadarajulu Naidu Challagundla Sai Gopal DVR Pasupuleti Visweswara Rao RS160-167 Pharmacognosy. Pharmaceutical substances (Plant, animal, and inorganic) The current investigation highlights the green synthesis of silver nanoparticles (AgNPs) by the insectivorous plant Drosera spatulata Labill var. bakoensis, which is the first of its kind. The biosynthesized nanoparticles revealed a UV visible surface plasmon resonance (SPR) band at 427 nm. The natural phytoconstituents which reduce the monovalent silver were identified by FTIR. The particle size of the Ds-AgNPs was detected by the Nanoparticle size analyzer confirms that the average size of nanoparticles was around 23 ± 2 nm. Ds-AgNPs exhibit high stability because of its high negative zeta potential (− 34.1 mV). AFM studies also revealed that the Ds-AgNPs were spherical in shape and average size ranges from 10 to 20 ± 5 nm. TEM analysis also revealed that the average size of Ds-AgNPs was also around 21 ± 4 nm and the shape is roughly spherical and well dispersed. The crystal nature of Ds-AgNPs was detected as a face-centered cube by the XRD analysis. Furthermore, studies on antibacterial and antifungal activities manifested outstanding antimicrobial activities of Ds-AgNPs compared with standard antibiotic Amoxyclav. In addition, demonstration of superior free radical scavenging efficacy coupled with potential in vitro cytotoxic significance on Human colon cancer cell lines (HT-29) suggests that the Ds-AgNPs attain excellent multifunctional therapeutic applications. Nature Publishing Group 2021 Article PeerReviewed text en https://eprints.ums.edu.my/id/eprint/31879/1/Multifaceted%20phytogenic%20silver%20nanoparticles%20by%20an%20insectivorous%20plant%20drosera%20spatulata%20Labill%20var.%20bakoensis%20and%20its%20potential%20therapeutic%20applications.pdf text en https://eprints.ums.edu.my/id/eprint/31879/2/Multifaceted%20phytogenic%20silver%20nanoparticles%20by%20an%20insectivorous%20plant%20drosera%20spatulata%20Labill%20var.%20bakoensis%20and%20its%20potential%20therapeutic%20applications_ABSTRACT.pdf Susmila Aparna Gaddam and Venkata Subbaiah Kotakadi and Gunasekhar Kalavakunta Subramanyam and Josthna Penchalaneni and Varadarajulu Naidu Challagundla and Sai Gopal DVR and Pasupuleti Visweswara Rao (2021) Multifaceted phytogenic silver nanoparticles by an insectivorous plant drosera spatulata Labill var. bakoensis and its potential therapeutic applications. Scientific Reports, 11. pp. 1-17. ISSN 2045-2322 https://www.nature.com/articles/s41598-021-01281-8.pdf?proof=t%25C2%25A0 https://doi.org/10.1038/s41598-021-01281-8 |
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RS160-167 Pharmacognosy. Pharmaceutical substances (Plant, animal, and inorganic) Susmila Aparna Gaddam Venkata Subbaiah Kotakadi Gunasekhar Kalavakunta Subramanyam Josthna Penchalaneni Varadarajulu Naidu Challagundla Sai Gopal DVR Pasupuleti Visweswara Rao Multifaceted phytogenic silver nanoparticles by an insectivorous plant drosera spatulata Labill var. bakoensis and its potential therapeutic applications |
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The current investigation highlights the green synthesis of silver nanoparticles (AgNPs) by the insectivorous plant Drosera spatulata Labill var. bakoensis, which is the first of its kind. The biosynthesized nanoparticles revealed a UV visible surface plasmon resonance (SPR) band at 427 nm. The natural phytoconstituents which reduce the monovalent silver were identified by FTIR. The particle size of the Ds-AgNPs was detected by the Nanoparticle size analyzer confirms that the average size of nanoparticles was around 23 ± 2 nm. Ds-AgNPs exhibit high stability because of its high negative zeta potential (− 34.1 mV). AFM studies also revealed that the Ds-AgNPs were spherical in shape and average size ranges from 10 to 20 ± 5 nm. TEM analysis also revealed that the average size of Ds-AgNPs was also around 21 ± 4 nm and the shape is roughly spherical and well dispersed. The crystal nature of Ds-AgNPs was detected as a face-centered cube by the XRD analysis. Furthermore, studies on antibacterial and antifungal activities manifested outstanding antimicrobial activities of Ds-AgNPs compared with standard antibiotic Amoxyclav. In addition, demonstration of superior free radical scavenging efficacy coupled with potential in vitro cytotoxic significance on Human colon cancer cell lines (HT-29) suggests that the Ds-AgNPs attain excellent multifunctional therapeutic applications. |
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Article |
author |
Susmila Aparna Gaddam Venkata Subbaiah Kotakadi Gunasekhar Kalavakunta Subramanyam Josthna Penchalaneni Varadarajulu Naidu Challagundla Sai Gopal DVR Pasupuleti Visweswara Rao |
author_facet |
Susmila Aparna Gaddam Venkata Subbaiah Kotakadi Gunasekhar Kalavakunta Subramanyam Josthna Penchalaneni Varadarajulu Naidu Challagundla Sai Gopal DVR Pasupuleti Visweswara Rao |
author_sort |
Susmila Aparna Gaddam |
title |
Multifaceted phytogenic silver nanoparticles by an insectivorous plant drosera spatulata Labill var. bakoensis and its potential therapeutic applications |
title_short |
Multifaceted phytogenic silver nanoparticles by an insectivorous plant drosera spatulata Labill var. bakoensis and its potential therapeutic applications |
title_full |
Multifaceted phytogenic silver nanoparticles by an insectivorous plant drosera spatulata Labill var. bakoensis and its potential therapeutic applications |
title_fullStr |
Multifaceted phytogenic silver nanoparticles by an insectivorous plant drosera spatulata Labill var. bakoensis and its potential therapeutic applications |
title_full_unstemmed |
Multifaceted phytogenic silver nanoparticles by an insectivorous plant drosera spatulata Labill var. bakoensis and its potential therapeutic applications |
title_sort |
multifaceted phytogenic silver nanoparticles by an insectivorous plant drosera spatulata labill var. bakoensis and its potential therapeutic applications |
publisher |
Nature Publishing Group |
publishDate |
2021 |
url |
https://eprints.ums.edu.my/id/eprint/31879/1/Multifaceted%20phytogenic%20silver%20nanoparticles%20by%20an%20insectivorous%20plant%20drosera%20spatulata%20Labill%20var.%20bakoensis%20and%20its%20potential%20therapeutic%20applications.pdf https://eprints.ums.edu.my/id/eprint/31879/2/Multifaceted%20phytogenic%20silver%20nanoparticles%20by%20an%20insectivorous%20plant%20drosera%20spatulata%20Labill%20var.%20bakoensis%20and%20its%20potential%20therapeutic%20applications_ABSTRACT.pdf https://eprints.ums.edu.my/id/eprint/31879/ https://www.nature.com/articles/s41598-021-01281-8.pdf?proof=t%25C2%25A0 https://doi.org/10.1038/s41598-021-01281-8 |
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