Acute and chronic rhinosinusitis, pathophysiology and treatment
Acute sinusitis (ARS) and chronic rhinosinusitis (CRS) is a common condition worldwide.CRS is due to the infection and inflammation of paranasal sinuses. Frequent clinical manifestations of ARS include persistent symptoms with nasal discharge or cough or both, presentation with fever accompanies pur...
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my.ums.eprints.275432021-06-30T12:33:32Z https://eprints.ums.edu.my/id/eprint/27543/ Acute and chronic rhinosinusitis, pathophysiology and treatment Murtaza Mustafa P. Patawari HM,Iftikhar SC.Shimmi SS.Hussain Mie, Mie Sein RA Public aspects of medicine Acute sinusitis (ARS) and chronic rhinosinusitis (CRS) is a common condition worldwide.CRS is due to the infection and inflammation of paranasal sinuses. Frequent clinical manifestations of ARS include persistent symptoms with nasal discharge or cough or both, presentation with fever accompanies purulent nasal discharge, and worsening symptoms. Complications of CRS have five stages, preseptal cellulitis, orbital cellulitis, subperiosteal abscess, orbital abscess and cavernous sinus septic thrombosis. Most acute sinusitis generally of viral origin, e,g. rhinoviruses, corona viruses,and influenza viruses. Bacterial pathogen include Streptococcus pneumonia, Haemophilus influenza and Moraxella catarrhalis. Bacteria found in biofilms have their antibiotic resistant increased up to 1000 times when compared to bacteria free living of same species. Sinusitis also results from fungal invasion in patients with diabetes, immune deficiencies, and AIDSor transplant patients. Bacterial and viral sinusitis are difficult to distinguish. The diagnosis of acute sinusitis should be on clinical presentation in most patients CT scan of sinuses is useful for patients with complications and in patients in whom sinus surgery is considered. MRI may have a role in the diagnosis of fungal rhinitis. The benefit of Functional Endoscopic Sinus Surgery (FESS) is its ability for a more targeted approach. Recently developed treatment by balloon sinuplasty is promising. A short-course of antibiotics is helpful in clinically diagnosed bacterial sinusitis without complicating factors. 2015 Article PeerReviewed text en https://eprints.ums.edu.my/id/eprint/27543/1/Acute%20and%20chronic%20rhinosinusitis%2C%20pathophysiology%20and%20treatment%20ABSTRACT.pdf text en https://eprints.ums.edu.my/id/eprint/27543/2/Acute%20and%20chronic%20rhinosinusitis%2C%20pathophysiology%20and%20treatment%20FULL%20TEXT.pdf Murtaza Mustafa and P. Patawari and HM,Iftikhar and SC.Shimmi and SS.Hussain and Mie, Mie Sein (2015) Acute and chronic rhinosinusitis, pathophysiology and treatment. International Journal of Pharmaceutical Science Invention, 4 (2). pp. 30-36. ISSN 2319 – 6718 http://ijpsi.org/Papers/Vol4(2)/D042030036.pdf |
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Acute sinusitis (ARS) and chronic rhinosinusitis (CRS) is a common condition worldwide.CRS is due to the infection and inflammation of paranasal sinuses. Frequent clinical manifestations of ARS include persistent symptoms with nasal discharge or cough or both, presentation with fever accompanies purulent nasal discharge, and worsening symptoms. Complications of CRS have five stages, preseptal cellulitis, orbital cellulitis, subperiosteal abscess, orbital abscess and cavernous sinus septic thrombosis. Most acute sinusitis generally of viral origin, e,g. rhinoviruses, corona viruses,and influenza viruses. Bacterial pathogen include Streptococcus pneumonia, Haemophilus influenza and Moraxella catarrhalis. Bacteria found in biofilms have their antibiotic resistant increased up to 1000 times when compared to bacteria free living of same species. Sinusitis also results from fungal invasion in patients with diabetes, immune deficiencies, and AIDSor transplant patients. Bacterial and viral sinusitis are difficult to distinguish. The diagnosis of acute sinusitis should be on clinical presentation in most patients CT scan of sinuses is useful for patients with complications and in patients in whom sinus surgery is considered. MRI may have a role in the diagnosis of fungal rhinitis. The benefit of Functional Endoscopic Sinus Surgery (FESS) is its ability for a more targeted approach. Recently developed treatment by balloon sinuplasty is promising. A short-course of antibiotics is helpful in clinically diagnosed bacterial sinusitis without complicating factors. |
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Article |
author |
Murtaza Mustafa P. Patawari HM,Iftikhar SC.Shimmi SS.Hussain Mie, Mie Sein |
author_facet |
Murtaza Mustafa P. Patawari HM,Iftikhar SC.Shimmi SS.Hussain Mie, Mie Sein |
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Murtaza Mustafa |
title |
Acute and chronic rhinosinusitis, pathophysiology and treatment |
title_short |
Acute and chronic rhinosinusitis, pathophysiology and treatment |
title_full |
Acute and chronic rhinosinusitis, pathophysiology and treatment |
title_fullStr |
Acute and chronic rhinosinusitis, pathophysiology and treatment |
title_full_unstemmed |
Acute and chronic rhinosinusitis, pathophysiology and treatment |
title_sort |
acute and chronic rhinosinusitis, pathophysiology and treatment |
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2015 |
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https://eprints.ums.edu.my/id/eprint/27543/1/Acute%20and%20chronic%20rhinosinusitis%2C%20pathophysiology%20and%20treatment%20ABSTRACT.pdf https://eprints.ums.edu.my/id/eprint/27543/2/Acute%20and%20chronic%20rhinosinusitis%2C%20pathophysiology%20and%20treatment%20FULL%20TEXT.pdf https://eprints.ums.edu.my/id/eprint/27543/ http://ijpsi.org/Papers/Vol4(2)/D042030036.pdf |
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