Network pharmacology and component analysis integrated study to unveil molecular mechanisms of a traditional chinese medicine decoction (polygonum multiflorum, rehmannia glutinosa, senna obtusifolia and crataegus) in hypertension treatment

• Main Authors: Lem, Fui Fui, Fernandes Opook, Fahcina P. Lawson, Yong, Wilson,Thau Lym, Chee, Fong Tyng
• Format: Article
• Language: English; English
• Published: Research Square
• Subjects: RA Public aspects of medicine
• Online Access: https://eprints.ums.edu.my/id/eprint/27017/1/Network%20pharmacology%20and%20component%20analysis%20integrated%20study%20to%20unveil%20molecular%20mechanisms%20of%20a%20traditional%20chinese%20medicine%20decoction%20.pdf; https://eprints.ums.edu.my/id/eprint/27017/2/Network%20pharmacology%20and%20component%20analysis%20integrated%20study%20to%20unveil%20molecular%20mechanisms%20of%20a%20traditional%20chinese%20medicine%20decoction%20FULLTEXT.pdf; https://eprints.ums.edu.my/id/eprint/27017/; https://doi.org/10.21203/rs.3.rs-37963/v1

Background: Traditional Chinese Medicines (TCM) are known for their curative effects on hypertension through a holistic approach. The molecular mechanisms of the formulation comprising Polygonum multiorum, Rehmannia glutinosa, Senna obtusifolia and Crataegus, used by Chinese practitioners in amelior...