Sarcoidosis and Corticosteroid Therapy: Dilemma from a Psychiatric Point of View
Introduction and Methods: A man diagnosed with sarcoidosis developed partial retrograde amnesia followed by three months of depressive symptoms with panic attacks, which remitted with an antidepressant and a benzodiazepine. However, three months later hallucinations and overvalued persecutory ideati...
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2021
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my.ums.eprints.269012021-05-05T00:35:02Z https://eprints.ums.edu.my/id/eprint/26901/ Sarcoidosis and Corticosteroid Therapy: Dilemma from a Psychiatric Point of View Mohd Amiruddin Mohd Kassim Ruziana Masiran Pang, Nicholas Tze Ping R Medicine (General) RA Public aspects of medicine Introduction and Methods: A man diagnosed with sarcoidosis developed partial retrograde amnesia followed by three months of depressive symptoms with panic attacks, which remitted with an antidepressant and a benzodiazepine. However, three months later hallucinations and overvalued persecutory ideations subsequently emerged, only to show partial response to antipsychotic treatment. Results: Sarcoidosis was treated with corticosteroids but serial thorax imaging shows minimal response. Corticosteroid was onboard throughout treatment, corresponding with non-remission of psychotic symptoms. There are persistent subjective cognitive difficulties but Mini Mental State Exam score is full. He is currently being treated with escitalopram, alprazolam and quetiapine. Conclusion: This case illustrated the dilemma between prolonging the corticosteroid therapy for sarcoidosis treatment and the psychiatric sequalae. While symptomatic antipsychotic treatment is effective, multi-disciplinary approach is imperative in determining the duration of the corticosteroid therapy. Archives of Psychiatry Research 2021 Article PeerReviewed text en https://eprints.ums.edu.my/id/eprint/26901/1/Sarcoidosis%20and%20Corticosteroid%20Therapy.pdf text en https://eprints.ums.edu.my/id/eprint/26901/2/Sarcoidosis%20and%20Corticosteroid%20Therapy1.pdf Mohd Amiruddin Mohd Kassim and Ruziana Masiran and Pang, Nicholas Tze Ping (2021) Sarcoidosis and Corticosteroid Therapy: Dilemma from a Psychiatric Point of View. Archives of Psychiatry Research, 57. pp. 93-98. ISSN 2671-2008 file:///C:/Users/user/Downloads/archives_vol_57_no_1_9%20(1).pdf |
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Introduction and Methods: A man diagnosed with sarcoidosis developed partial retrograde amnesia followed by three months of depressive symptoms with panic attacks, which remitted with an antidepressant and a benzodiazepine. However, three months later hallucinations and overvalued persecutory ideations subsequently emerged, only to show partial response to antipsychotic treatment. Results: Sarcoidosis was treated with corticosteroids but serial thorax imaging shows minimal response. Corticosteroid was onboard throughout treatment, corresponding with non-remission of psychotic symptoms. There are persistent subjective cognitive difficulties but Mini Mental State Exam score is full. He is currently being treated with escitalopram, alprazolam and quetiapine. Conclusion: This case illustrated the dilemma between prolonging the corticosteroid therapy for sarcoidosis treatment and the psychiatric sequalae. While symptomatic antipsychotic treatment is effective, multi-disciplinary approach is imperative in determining the duration of the corticosteroid therapy. |
format |
Article |
author |
Mohd Amiruddin Mohd Kassim Ruziana Masiran Pang, Nicholas Tze Ping |
author_facet |
Mohd Amiruddin Mohd Kassim Ruziana Masiran Pang, Nicholas Tze Ping |
author_sort |
Mohd Amiruddin Mohd Kassim |
title |
Sarcoidosis and Corticosteroid Therapy: Dilemma from a Psychiatric Point of View |
title_short |
Sarcoidosis and Corticosteroid Therapy: Dilemma from a Psychiatric Point of View |
title_full |
Sarcoidosis and Corticosteroid Therapy: Dilemma from a Psychiatric Point of View |
title_fullStr |
Sarcoidosis and Corticosteroid Therapy: Dilemma from a Psychiatric Point of View |
title_full_unstemmed |
Sarcoidosis and Corticosteroid Therapy: Dilemma from a Psychiatric Point of View |
title_sort |
sarcoidosis and corticosteroid therapy: dilemma from a psychiatric point of view |
publisher |
Archives of Psychiatry Research |
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2021 |
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https://eprints.ums.edu.my/id/eprint/26901/1/Sarcoidosis%20and%20Corticosteroid%20Therapy.pdf https://eprints.ums.edu.my/id/eprint/26901/2/Sarcoidosis%20and%20Corticosteroid%20Therapy1.pdf https://eprints.ums.edu.my/id/eprint/26901/ |
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