ATP gatekeeper of Plasmodium protein kinase may provide the opportunity to develop selective antimalarial drugs with multiple targets

• Main Authors: Fauze Mahmud, Lee, Ping Chin, Wahab, H., Mustaffa, K.F., Leow, C.H., Rasul, A., Lai, N.S.
• Format: Article
• Language: English
• Published: 2020
• Subjects: Q Science (General)
• Online Access: https://eprints.ums.edu.my/id/eprint/26332/1/ATP%20gatekeeper%20of%20Plasmodium%20protein%20kinase%20may%20provide%20the%20opportunity%20to%20develop%20selective%20antimalarial%20drugs%20with%20multiple%20targets.pdf; https://eprints.ums.edu.my/id/eprint/26332/

Malaria is one of the most devastating infectious diseases that caused millions of clinical cases annually despite decades of prevention efforts. Recent cases of Plasmodium falciparum resistance against the only remaining class of effective antimalarial (artemisinin) in South East Asia may soon pose...