Advanced Triple Negative Breast Cancer in Pregnancy

Breast cancer is one of the most common prevalent malignancies in pregnancy. The management is challenging as it involves both maternal and fetal well-being. A 41-year-old lady was diagnosed with triple negative breast cancer in the second trimester pregnancy. Neoadjuvant chemotherapy was decided as...

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Bibliographic Details
Main Authors: Tze Huat Chong, Gunaseelan G. Durairaj, Firdaus Hayati, Nornazirah Azizan, Fatimah Ahmedy, Nor Faezan Abdul Rashid
Format: Article
Language:English
English
Published: 2020
Subjects:
Online Access:https://eprints.ums.edu.my/id/eprint/26305/1/Advanced%20Triple%20Negative%20Breast%20Cancer%20in%20Pregnancy.pdf
https://eprints.ums.edu.my/id/eprint/26305/2/Advanced%20Triple%20Negative%20Breast%20Cancer%20in%20Pregnancy1.pdf
https://eprints.ums.edu.my/id/eprint/26305/
http://dx.doi.org/10.12996/gmj.2020.153
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Summary:Breast cancer is one of the most common prevalent malignancies in pregnancy. The management is challenging as it involves both maternal and fetal well-being. A 41-year-old lady was diagnosed with triple negative breast cancer in the second trimester pregnancy. Neoadjuvant chemotherapy was decided as she opted for a continuation of pregnancy and refusal for mastectomy. After completing the second cycle of chemotherapy, she developed preterm premature rupture of membrane and had fetal malposition requiring an emergency caesarean section. Computed tomography staging revealed an advanced disease, hence needing palliative treatment and support. The difficulties in managing this case arise in choosing the best treatment to preserve both maternal and fetal wellbeing.