16-Hydroxycembra-1,3,7,11-tetraene, a new Cembrane Diterpene from Malaysian Soft Coral Genus Sarcophyton

One new cembrane diterpene, 16-hydroxycembra-1,3,7,11-tetraene (1), along with three known compounds, 15-hydroxycembra-1,3,7,11-tetraene (2), sarcophine (3) and sarcophytoxide (4) were isolated from Sarcophyton sp. collected from Karah Island, Terengganu, West Malaysia. Their structures were elucida...

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Bibliographic Details
Main Authors: Takashi Kamada, Chin-Soon Phan, Tin, Hoe Seng, Charles Santhanaraju Vairappan, TengkuSifzizul Tengku Muhammad
Format: Article
Language:English
English
Published: 2016
Subjects:
Online Access:https://eprints.ums.edu.my/id/eprint/25557/1/16-Hydroxycembra-1%2C3%2C7%2C11-tetraene%2C%20a%20new%20Cembrane%20Diterpene%20from%20Malaysian%20Soft%20Coral%20Genus%20Sarcophyton.pdf
https://eprints.ums.edu.my/id/eprint/25557/2/16-Hydroxycembra-1%2C3%2C7%2C11-tetraene%2C%20a%20new%20Cembrane%20Diterpene%20from%20Malaysian%20Soft%20Coral%20Genus%20Sarcophyton1.pdf
https://eprints.ums.edu.my/id/eprint/25557/
https://doi.org/10.1177/1934578X1601100810
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Summary:One new cembrane diterpene, 16-hydroxycembra-1,3,7,11-tetraene (1), along with three known compounds, 15-hydroxycembra-1,3,7,11-tetraene (2), sarcophine (3) and sarcophytoxide (4) were isolated from Sarcophyton sp. collected from Karah Island, Terengganu, West Malaysia. Their structures were elucidated based on spectroscopic data. Activities of these compounds against antibacterial resistant clinical bacteria are reported. Only 1 exhibited inhibition against Staphylococcus aureus.