Accumulation of physalin in cells and tissues of Physalis minima

• Main Authors: Gansau Jualang Azlan, M. Marziah, M. Radzali, Ruchi Johari
• Format: Article
• Language: English; English
• Subjects: RS Pharmacy and materia medica
• Online Access: https://eprints.ums.edu.my/id/eprint/21484/1/Accumulation%20of%20physalin%20in%20cells%20and%20tissues%20of%20Physalis%20minima.pdf; https://eprints.ums.edu.my/id/eprint/21484/2/Accumulation%20of%20physalin%20in%20cells%20and%20tissues%20of%20Physalis%20minima.pdf; https://eprints.ums.edu.my/id/eprint/21484/

Accumulation of physalin was investigated in the intact tissues of P. minima at different developmental growth stages and locations and compared with that in cell cultures. Results showed that this compound was mainly accumulated in mature plants, that is higher physalin content was observed in fruiting plants flowering and juvenile plants. Different tissues were also observed to vary in the physalin accumulation. Physalin A was mostly accumulated in the young fruit, physalin B in the young leaf and flower bud, physalin D in the flower bud, physalin F in the mature leaf, physalin J in the immature and ripe fruit calyx, and physalin N in the leaf tissues. The content of physalin in intact plant tissues varied from 0.07 to 9.89 mg g-1 DW. Physalin yield in the fruit was mainly located in the seeds. Physalin accumulation in specific tissues of a particular plant, however appeared to be greatly affected by environmental and geographical factors. The accumulation levels of physalin in cell cultures were 2.2-11.5 folds lower than that in intact plant tissues.