Oxidative stress biomarkers in organs of hyperlipidaemic and natural rats fed tropical red seaweed, Gracilaria changii
The aim of the study was to evaluate the effects of normal and high-cholesterol/fat diet supplemented with 5 and 10% freeze-dried red seaweed, Gracilaria changii powder on rat organs (liver, kidney and heart), lipid peroxidation and antioxidant enzyme activities. The results showed that feeding wit...
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my.ums.eprints.195572018-04-03T01:38:03Z https://eprints.ums.edu.my/id/eprint/19557/ Oxidative stress biomarkers in organs of hyperlipidaemic and natural rats fed tropical red seaweed, Gracilaria changii Pei, Teng Chan Patricia Matanjun Suhaimi Md Yasir Tan, Tek Song SH Aquaculture. Fisheries. Angling The aim of the study was to evaluate the effects of normal and high-cholesterol/fat diet supplemented with 5 and 10% freeze-dried red seaweed, Gracilaria changii powder on rat organs (liver, kidney and heart), lipid peroxidation and antioxidant enzyme activities. The results showed that feeding with atherogenic diet alone caused lipid peroxidation which eventually leads to oxidative stress of the rat’s organs. Nevertheless, with 10 % G. changii supplementation, it significantly decreased the liver lipid peroxidation by 52.24 %, and the antioxidant enzyme activities were significantly increased by 52.09 to 94.42 %. Similarly, with G. changii supplementation, it significantly enhanced the kidney antioxidant enzyme activities. This suggests that G. changii suppress oxidative stress and protect the rats’ organs. In conclusion, G. changii could be a promising functional food ingredient in the management of hyperlipidaemia. Springer 2016 Article PeerReviewed text en https://eprints.ums.edu.my/id/eprint/19557/1/Oxidative%20stress%20biomarkers%20in%20organs%20of%20hyperlipidaemic%20and%20natural%20rats%20fed%20tropical%20red%20seaweed.pdf Pei, Teng Chan and Patricia Matanjun and Suhaimi Md Yasir and Tan, Tek Song (2016) Oxidative stress biomarkers in organs of hyperlipidaemic and natural rats fed tropical red seaweed, Gracilaria changii. Journal of Applied Phycology, 28. pp. 1371-1378. ISSN 0921-8971 |
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SH Aquaculture. Fisheries. Angling Pei, Teng Chan Patricia Matanjun Suhaimi Md Yasir Tan, Tek Song Oxidative stress biomarkers in organs of hyperlipidaemic and natural rats fed tropical red seaweed, Gracilaria changii |
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The aim of the study was to evaluate the effects of
normal and high-cholesterol/fat diet supplemented with 5 and 10% freeze-dried red seaweed, Gracilaria changii powder on rat organs (liver, kidney and heart), lipid peroxidation and antioxidant enzyme activities. The results showed that feeding with atherogenic diet alone caused lipid peroxidation which eventually leads to oxidative stress of the rat’s organs. Nevertheless, with 10 % G. changii supplementation, it significantly decreased the liver lipid peroxidation by 52.24 %, and the antioxidant enzyme activities were significantly increased by 52.09 to 94.42 %. Similarly, with G. changii supplementation, it significantly enhanced the kidney antioxidant enzyme activities. This
suggests that G. changii suppress oxidative stress and protect the rats’ organs. In conclusion, G. changii could be a promising functional food ingredient in the management of
hyperlipidaemia. |
format |
Article |
author |
Pei, Teng Chan Patricia Matanjun Suhaimi Md Yasir Tan, Tek Song |
author_facet |
Pei, Teng Chan Patricia Matanjun Suhaimi Md Yasir Tan, Tek Song |
author_sort |
Pei, Teng Chan |
title |
Oxidative stress biomarkers in organs of hyperlipidaemic and natural rats fed tropical red seaweed, Gracilaria changii |
title_short |
Oxidative stress biomarkers in organs of hyperlipidaemic and natural rats fed tropical red seaweed, Gracilaria changii |
title_full |
Oxidative stress biomarkers in organs of hyperlipidaemic and natural rats fed tropical red seaweed, Gracilaria changii |
title_fullStr |
Oxidative stress biomarkers in organs of hyperlipidaemic and natural rats fed tropical red seaweed, Gracilaria changii |
title_full_unstemmed |
Oxidative stress biomarkers in organs of hyperlipidaemic and natural rats fed tropical red seaweed, Gracilaria changii |
title_sort |
oxidative stress biomarkers in organs of hyperlipidaemic and natural rats fed tropical red seaweed, gracilaria changii |
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Springer |
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2016 |
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https://eprints.ums.edu.my/id/eprint/19557/1/Oxidative%20stress%20biomarkers%20in%20organs%20of%20hyperlipidaemic%20and%20natural%20rats%20fed%20tropical%20red%20seaweed.pdf https://eprints.ums.edu.my/id/eprint/19557/ |
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