Polyplexes and Lipoplexes for mammalian gene delivery: from traditional to Microarray screening

• Main Authors: How, Siew Eng, Boon-ek Yingyongnarongkul, Fara, M. A., Juan J Diaz-Mochon, Mittoo, S., Mark Bradley
• Format: Article
• Language: English
• Published: 2004
• Subjects: QP Physiology
• Online Access: https://eprints.ums.edu.my/id/eprint/19309/1/Polyplexes%20and%20Lipoplexes%20for%20mammalian%20gene%20delivery.pdf; https://eprints.ums.edu.my/id/eprint/19309/; http://dx.doi.org/10.2174/1386207043328616

Gene therapy requires the development of non-toxic and highly efficient delivery systems for DNA and RNAi. Polycations, especially dendrimers, have shown enormous potential as gene transfer vehicles, displaying minimal toxicity with a broad range of cell lines. In this paper, a total of 13 dendrimer...