Anti-malarial activities of two actinomycete isolates from sabah soil involved inhibition of glycogen synthase kinase 3ß

• Main Authors: Dhiana Efani Dahari, Raifana Mohamad Salleh, Fauze Mahmud, Lee, Ping Chin, Noor Embi, Hasidah Mohd Sidek
• Format: Article
• Language: English; English
• Published: Universiti Sains Malaysia 2016
• Subjects: RC Internal medicine
• Online Access: https://eprints.ums.edu.my/id/eprint/18888/1/Anti_Malarial.pdf; https://eprints.ums.edu.my/id/eprint/18888/7/Anti-malarial%20Activities%20of%20Two%20Soil%20Actinomycete%20Isolates%20from%20Sabah%20via.pdf; https://eprints.ums.edu.my/id/eprint/18888/; http://www.tlsr.usm.my/tlsr27022016/27022016_05.pdf

Exploiting natural resources for bioactive compounds is an attractive drug discovery strategy in search for new anti-malarial drugs with novel modes of action. Initial screening efforts in our laboratory revealed two preparations of soil-derived actinomycetes (H11809 and FH025) with potent anti-mala...