afsS is a target of AfsR, a transcriptional factor with ATPase activity that globally controls secondary metabolism in Streptmyces coelicolor A3(2)

• Main Authors: Lee, Ping Chin, Umeyama Takashi, Horinouchi Sueharu
• Format: Article
• Language: English
• Published: John Wiley & Sons Ltd 2002
• Subjects: QR Microbiology
• Online Access: https://eprints.ums.edu.my/id/eprint/18837/1/afsS%20is%20a%20target%20of%20AfsR.pdf; https://eprints.ums.edu.my/id/eprint/18837/; http://doi.org/10.1046/j.1365-2958.2002.02840.x

AfsR is a pleiotropic, global regulator that controls the production of actinorhodin, undecylprodigiosin and calcium-dependent antibiotic in Streptomyces coelicolor A3(2). AfsR, with 993 amino acids, is phosphorylated on serine and threonine residues by a protein serine/threonine kinase AfsK and con...