Three new cembranoids from the Bornean soft coral Nephthea sp.

Three new cembranoid diterpenes, 10-hydroxy-nephthenol acetate (1), 7,8-epoxy-10-hydroxy-nephthenol acetate (2), and 6-acetoxy-7,8-epoxy-10-hydroxy-nephthenol acetate (3), along with a known compound, 6-acetoxy-7,8-epoxy-nephthenol acetate (4), were isolated from the Bornean soft coral Nephthea sp....

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Bibliographic Details
Main Authors: Charles Santhanaraju Vairappan, Takashi Kamada, Takashiro Ishii
Format: Article
Language:English
Published: Taylor & Francis Group 2016
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Online Access:https://eprints.ums.edu.my/id/eprint/13798/1/Three_new_cembranoids_from_the_Bornean_soft_coral_Nephthea_sp.pdf
https://eprints.ums.edu.my/id/eprint/13798/
http://dx.doi.org/10.1080/10286020.2016.1145670
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Summary:Three new cembranoid diterpenes, 10-hydroxy-nephthenol acetate (1), 7,8-epoxy-10-hydroxy-nephthenol acetate (2), and 6-acetoxy-7,8-epoxy-10-hydroxy-nephthenol acetate (3), along with a known compound, 6-acetoxy-7,8-epoxy-nephthenol acetate (4), were isolated from the Bornean soft coral Nephthea sp. Antibacterial and anticancer activities were exhibited by compounds 1 and 2 against Staphylococcus aureus (ATCC 6538)/Escherichia coli (ATCC 13311) and Hela/MCF-7, respectively.