In Vitro Study Of The Effect Of Corn Silk On Glucose Uptake By Isolated Rat Hemi-Diaphragm

• Main Authors: Nour, A. H., M., Ghada, Eltohami, M. S., Mudawi, Mahmoud M. E.
• Format: Article
• Language: English
• Published: WJPR, Medical University, Bulgaria 2014
• Subjects: TP Chemical technology
• Online Access: http://umpir.ump.edu.my/id/eprint/6598/1/In_Vitro_Study_Of_The_Effect_Of_Corn_Silk_On_Glucose_Uptake_By_Isolated_Rat_Hemi-Diaphragm.pdf; http://umpir.ump.edu.my/id/eprint/6598/; http://www.wjpr.net/dashboard/abstract_id/1094#

In the present study the methanolic extract of corn silk was evaluated for antidiabetic activity. The antidiabetic activity was studied using the glucose uptake by isolated rat hemi-diaphragm using in-vitro model. Corn silk increased the uptake of glucose by isolated rat hemidiaphragm significantly (P<0.001) and was found to be more effective than insulin. It appears that corn silk has direct peripheral action on glucose uptake. The value of glucose uptake by rat hemi-diaphragm after addition of corn silk extract was 109±1 as compared to control (12± 1) and Insulin (49 ± 8)mg/g/30min .These results strongly suggest that Corn silk will be alternative choice for the treatment of diabetes mellitus.