Estrogenic post-menopausal anti-osteoporotic mechanism of Achyranthes aspera L.: Phytochemicals and network pharmacology approaches

• Main Authors: Moyeenul Huq, A. K. M., Stanslas, Johnson, Nizhum, Nisarat, Uddin, Md. Nazim, Maulidiani, Maulidiani, Roney, Miah, Faridah, Abas, Jamal, Jamia Azdina
• Format: Article
• Language: English
• Published: Elsevier Ltd 2024
• Subjects: Q Science (General); RM Therapeutics. Pharmacology; TP Chemical technology
• Online Access: http://umpir.ump.edu.my/id/eprint/42974/1/Estrogenic%20post-menopausal%20anti-osteoporotic%20mechanism%20of%20Achyranthes%20aspera%20L..pdf; http://umpir.ump.edu.my/id/eprint/42974/; https://doi.org/10.1016/j.heliyon.2024.e38792; https://doi.org/10.1016/j.heliyon.2024.e38792

Hormone replacement therapy is used to treat postmenopausal syndrome caused by estrogen deficiency, but it has been linked to an increased risk of breast cancer. In India, Achyranthes aspera L. is traditionally used to treat menstrual problems; however, there is a lack of mechanistic evidence of its...