Mefenamic acid inhibit transforming growth factor-beta type-1: Repurposing anti-inflammatory drugs in wound healing using in-silico approaches

• Main Authors: Roney, Miah, Issahaku, Abdul Rashid, Normaiza, Zamri, Mohd Fadhlizil Fasihi, Mohd Aluwi
• Format: Article
• Language: English
• Published: Elsevier B.V. 2023
• Subjects: HD Industries. Land use. Labor; R Medicine (General)
• Online Access: http://umpir.ump.edu.my/id/eprint/41783/1/Mefenamic%20acid%20inhibit%20transforming%20growth%20factor-beta%20type-1%20-%20Repurposing%20anti-inflammatory%20drugs%20in%20wound%20healing%20using%20in-silico%20approaches.pdf; http://umpir.ump.edu.my/id/eprint/41783/; https://doi.org/10.1016/j.amolm.2023.100031

Due to low cost and time-saving benefits, drug repurposing is a safe and successful method to discover drug. A druggable target for inflammation, transforming growth factor-beta type-1 (TGF-β 1) has been identified to be associated with wound healing. Finding the most effective TGF-β 1 inhibitor amo...