Optimization of carboxymethyl cellulose-gum Arab-based hydrogel beads for anticancer drugs delivery

• Main Authors: Ghawanmeh, Abdullah A., Tan, Ling Ling, Ali, Gomaa A.M., Assiri, Mohammed Ali, Chong, Kwok Feng
• Format: Article
• Language: English; English
• Published: Elsevier B.V. 2024
• Subjects: HD28 Management. Industrial Management; Q Science (General); T Technology (General)
• Online Access: http://umpir.ump.edu.my/id/eprint/39986/1/Optimization%20of%20carboxymethyl%20cellulose-gum%20Arab-based%20hydrogel%20beads.pdf; http://umpir.ump.edu.my/id/eprint/39986/2/Optimization%20of%20carboxymethyl%20cellulose-gum%20Arab-based%20hydrogel%20beads%20for%20anticancer%20drugs%20delivery_ABS.pdf; http://umpir.ump.edu.my/id/eprint/39986/; https://doi.org/10.1016/j.molliq.2023.123631; https://doi.org/10.1016/j.molliq.2023.123631

Response surface methodology was successfully utilized to optimize the amounts of carboxymethyl cellulose (CMC) and gum Arab (GA) to fabricate hydrogel beads for the delivery of anticancer drugs. Drug encapsulation efficiency process (%DEE) and cumulative release (%R8h) of hydrogel beads were invest...