Marked gut microbiota dysbiosis and increased imidazole propionate are associated with a NASH Göttingen Minipig model

• Main Authors: Ditte Olsen, Lützhøft, Tim, Sinioja, Berit Ø., Christoffersen, Jakobsen, Rasmus Riemer, Dawei, Geng, Hajar Fauzan, Ahmad, Ellen Marie, Straarup, Karen-Margrethe, Pedersen, Kot, Witold, Henrik Duelund, Pedersen, Susanna, Cirera, Tuulia, Hyötyläinen, Dennis Sandris, Nielsen, Axel Kornerup, Hansen
• Format: Article
• Language: English
• Published: Springer Science and Business Media LLC 2022
• Subjects: HD Industries. Land use. Labor; Q Science (General)
• Online Access: http://umpir.ump.edu.my/id/eprint/38074/1/minipig.pdf; http://umpir.ump.edu.my/id/eprint/38074/; https://doi.org/10.1186%2Fs12866-022-02704-w

Background: Gut microbiota dysbiosis is associated with the development of non‑alcoholic steatohepatitis (NASH) through modulation of gut barrier, inflammation, lipid metabolism, bile acid signaling and short‑chain fatty acid production. The aim of this study was to describe the impact of a choline‑...