In vitro safety & quality analysis on three species of Tongkat Ali plants & their in vivo elevation of testosterone in fowls

Eurycoma longifolia, Polyathia bullata, and Stema tuberosa are three species of plants sharing the synonym of "Tongkat Ali" and commonly known as Tongkat Ali Putih, Tongkat Ali Hitam, and Tongkat Ali Merah, respectively. However, less study has been done on its effectiveness to increase te...

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Main Authors: Sharifah Aminah, Tuan Said, Jaya Vejayan, Palliah, Yasmin Amirah, Che Yahya
Format: Article
Language:English
Published: Penerbit Universiti Malaysia Pahang 2023
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Online Access:http://umpir.ump.edu.my/id/eprint/37974/1/document-2.pdf
http://umpir.ump.edu.my/id/eprint/37974/
https://doi.org/10.15282/cst.v2i2.9293
https://doi.org/10.15282/cst.v2i2.9293
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spelling my.ump.umpir.379742023-07-14T07:42:51Z http://umpir.ump.edu.my/id/eprint/37974/ In vitro safety & quality analysis on three species of Tongkat Ali plants & their in vivo elevation of testosterone in fowls Sharifah Aminah, Tuan Said Jaya Vejayan, Palliah Yasmin Amirah, Che Yahya Q Science (General) R Medicine (General) RV Botanic, Thomsonian, and eclectic medicine Eurycoma longifolia, Polyathia bullata, and Stema tuberosa are three species of plants sharing the synonym of "Tongkat Ali" and commonly known as Tongkat Ali Putih, Tongkat Ali Hitam, and Tongkat Ali Merah, respectively. However, less study has been done on its effectiveness to increase testosterone by P. bullata and S. tuberosa compared to E. longifolia. In this study, all three types of Tongkat Ali were compared for their testosterone elevations in fowls. The roots of the plants were encapsulated and given to fowls. Before being tested on animals, the capsules' content was analyzed on a few safety and quality parameters, i.e., pH and moisture tests, heavy metal content, microbial load, and steroid presence. A total of 12 mg of each Tongkat Ali powdered material included in a capsule and given to 14 fowls for 30 days. The outcome showed an increase in testosterone in fowls with the highest value of 9.73 ± 1.20 nmol/L obtained by P. bullata, followed by E. longifolia and S. tuberosa, 7.70 ± 0.59 nmol/L, and 6.25 ± 0.70 nmol/L, respectively compared to the control of only 4.08 ± 0.85 nmol/L. The results showed that P. bullata and S. tuberosa were safe to consume (in vitro) and able to increase testosterone level in the fowls (in vivo). Thus, it also provide added information on the less studied Tongkat Ali plants and their potential as an aphrodisiac plants. Penerbit Universiti Malaysia Pahang 2023-06-15 Article PeerReviewed pdf en cc_by_4 http://umpir.ump.edu.my/id/eprint/37974/1/document-2.pdf Sharifah Aminah, Tuan Said and Jaya Vejayan, Palliah and Yasmin Amirah, Che Yahya (2023) In vitro safety & quality analysis on three species of Tongkat Ali plants & their in vivo elevation of testosterone in fowls. Current Science and Technology (CST), 2 (2). pp. 35-41. ISSN 2785-8804. (Published) https://doi.org/10.15282/cst.v2i2.9293 https://doi.org/10.15282/cst.v2i2.9293
institution Universiti Malaysia Pahang
building UMP Library
collection Institutional Repository
continent Asia
country Malaysia
content_provider Universiti Malaysia Pahang
content_source UMP Institutional Repository
url_provider http://umpir.ump.edu.my/
language English
topic Q Science (General)
R Medicine (General)
RV Botanic, Thomsonian, and eclectic medicine
spellingShingle Q Science (General)
R Medicine (General)
RV Botanic, Thomsonian, and eclectic medicine
Sharifah Aminah, Tuan Said
Jaya Vejayan, Palliah
Yasmin Amirah, Che Yahya
In vitro safety & quality analysis on three species of Tongkat Ali plants & their in vivo elevation of testosterone in fowls
description Eurycoma longifolia, Polyathia bullata, and Stema tuberosa are three species of plants sharing the synonym of "Tongkat Ali" and commonly known as Tongkat Ali Putih, Tongkat Ali Hitam, and Tongkat Ali Merah, respectively. However, less study has been done on its effectiveness to increase testosterone by P. bullata and S. tuberosa compared to E. longifolia. In this study, all three types of Tongkat Ali were compared for their testosterone elevations in fowls. The roots of the plants were encapsulated and given to fowls. Before being tested on animals, the capsules' content was analyzed on a few safety and quality parameters, i.e., pH and moisture tests, heavy metal content, microbial load, and steroid presence. A total of 12 mg of each Tongkat Ali powdered material included in a capsule and given to 14 fowls for 30 days. The outcome showed an increase in testosterone in fowls with the highest value of 9.73 ± 1.20 nmol/L obtained by P. bullata, followed by E. longifolia and S. tuberosa, 7.70 ± 0.59 nmol/L, and 6.25 ± 0.70 nmol/L, respectively compared to the control of only 4.08 ± 0.85 nmol/L. The results showed that P. bullata and S. tuberosa were safe to consume (in vitro) and able to increase testosterone level in the fowls (in vivo). Thus, it also provide added information on the less studied Tongkat Ali plants and their potential as an aphrodisiac plants.
format Article
author Sharifah Aminah, Tuan Said
Jaya Vejayan, Palliah
Yasmin Amirah, Che Yahya
author_facet Sharifah Aminah, Tuan Said
Jaya Vejayan, Palliah
Yasmin Amirah, Che Yahya
author_sort Sharifah Aminah, Tuan Said
title In vitro safety & quality analysis on three species of Tongkat Ali plants & their in vivo elevation of testosterone in fowls
title_short In vitro safety & quality analysis on three species of Tongkat Ali plants & their in vivo elevation of testosterone in fowls
title_full In vitro safety & quality analysis on three species of Tongkat Ali plants & their in vivo elevation of testosterone in fowls
title_fullStr In vitro safety & quality analysis on three species of Tongkat Ali plants & their in vivo elevation of testosterone in fowls
title_full_unstemmed In vitro safety & quality analysis on three species of Tongkat Ali plants & their in vivo elevation of testosterone in fowls
title_sort in vitro safety & quality analysis on three species of tongkat ali plants & their in vivo elevation of testosterone in fowls
publisher Penerbit Universiti Malaysia Pahang
publishDate 2023
url http://umpir.ump.edu.my/id/eprint/37974/1/document-2.pdf
http://umpir.ump.edu.my/id/eprint/37974/
https://doi.org/10.15282/cst.v2i2.9293
https://doi.org/10.15282/cst.v2i2.9293
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score 13.160551