Ibuprofen-loaded chitosan–lipid nanoconjugate hydrogel with gum arabic: Green synthesis, characterisation, in vitro kinetics mechanistic release study and PGE2 production test

• Main Authors: Mahmood, Syed, Almurisi, Samah Hamed, AL-japairai, Khater Ahmed Saeed, Hilles, Ayah Rebhi, Alelwani, Walla, Bannunah, Azzah M., Alshammari, Farhan, Alheibshy, Fawaz
• Format: Article
• Language: English
• Published: MDPI 2021
• Subjects: TP Chemical technology
• Online Access: http://umpir.ump.edu.my/id/eprint/33080/1/Ibuprofen-loaded%20chitosan%E2%80%93lipid%20nanoconjugate%20hydrogel%20with%20gum%20arabic_Green%20synthesis.pdf; http://umpir.ump.edu.my/id/eprint/33080/; https://doi.org/10.3390/gels7040254; https://doi.org/10.3390/gels7040254

Ibuprofen is a well-known non-steroidal anti-inflammatory (NSAID) medicine that is often used to treat inflammation in general. When given orally, it produces gastrointestinal issues which lead to lower patient compliance. Ibuprofen transdermal administration improves both patient compliance and the...