Possible participation of ionotropic glutamate receptors and L-arginine-nitric oxide-cyclic guanosine monophosphate-ATP-sensitive K+ channel pathway in the antinociceptive activity of cardamonin in acute pain animal models

• Main Authors: Chung, Pui Ping, Akhtar, Muhammad Nadeem, Daud, Ahmad Israf, Perimal, Enoch Kumar, Mohd Roslan, Sulaiman
• Format: Article
• Language: English
• Published: MDPI - Open Access Publishing 2020
• Subjects: TP Chemical technology
• Online Access: http://umpir.ump.edu.my/id/eprint/31393/1/Possible%20participation%20of%20ionotropic%20glutamate%20receptors%20and%20i-arginine.pdf; http://umpir.ump.edu.my/id/eprint/31393/; https://doi.org/10.3390/molecules25225385; https://doi.org/10.3390/molecules25225385

The perception of pain caused by inflammation serves as a warning sign to avoid further injury. The generation and transmission of pain impulses involves various pathways and receptors. Cardamonin isolated from Boesenbergia rotunda (L.) Mansf. has been reported to exert antinociceptive effects in th...